Dr.sara nabil
Cairo, Egypt
Location status: Recruiting
Recruiting
NCT Number: NCT05473858
Oraverse Versus Laser
clinically assess the reversal of articaine 4% of two different concentration of vasoconcentration soft-tissue local anesthesia in pediatric dentistry using Diode Laser and Oraverse
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
6 year–10 year
Sex eligibility
All sexes
Study type
Interventional
Phase
Phase 3
Primary location
About this study
Patients will be divided randomly into two groups (20 patients in each group) Group (1): Patients will be undergoing anesthesia revision by diode laser Group (2): Patients will be undergoing anesthesia revision by oraverse. Then each group will be subdivided into 2 subgroups (10 patients each) according to type of local anesthetic agent into:
subgroup 1: Articaine 4% with 1:100000 epinephrin &Subgroup 2: Articaine 4% with 1:200000 epinephrin After 30 min of injection corresponding to approximate time of treatment, the patient in each group will be exposed to the reversal agent which may be diode laser or oraverse.
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Patients who need to be treated under anesthesia by injecting mandibular first molar infiltration.
- Cooperative children aged 6 to 10 years old with the ability to understand and respond to the sensation of soft tissue -
Treatment and study plan
OraVerse Injectable Product
Druginjection of oraverse,
Diode laser
Devicepatient exposed to diode laser
Anaesthesia only
OtherPatient exposed to anaesthesia without any more intervention
Primary outcomes
-
reversal of local anasthesia
Time frame: 30 minute
patient free of lip numbness
Study contacts
Contact information is provided by the study sponsor or research team.
Sponsors and collaborators
Lead sponsor
sara nabil
Other
Registry information
Official study title
Comparative Study of the Effect of Diode Laser and Oraverse on Reversing the Effect of Articaine 4% Soft Tissue Anasthesia in Children
Acronym: RCT
Important dates
- Study start
- 2021
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Jul 26, 2022
- Registry last updated
- Apr 6, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.