Oral Glucose Tolerance Testing After Gestational Diabetes

This is an observation study of women with gestational diabetes. Subjects recruited undergo immediate postpartum diabetic screening prior to discharge. Post-partum screening for overt diabetes is repeated 6-12 weeks postpartum. The outcome of interest is the utility of an immediate post partum screen for overt diabetes compared to a traditional 6 week test.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Gestational Diabetes Body Weight Diabetes Mellitus Diabetes, Gestational Endocrine System Diseases Female Urogenital Diseases and Pregnancy Complications Glucose Metabolism Disorders Metabolic Diseases Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Pregnancy Pregnancy Complications Signs and Symptoms Urogenital Diseases

Age range

18 year and older

Sex eligibility

Female

Study type

Observational

Primary location

MetroHealth Medical Center, Cleveland, Ohio, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Singleton pregnancy
Gestational diabetes

Exclusion criteria

Multiple gestations
pre-pregnancy diabetes

Treatment and study plan

Primary outcomes

Primary outcome: sensitivity of immediate post partum screen

Time frame: Immediate post partum

2 hour fasting 75g OGTT immediately post partum. This is compared to a traditional 6 week post partum 75g OGTT for the sensitivity, positive and negative predictive value of the immediate post partum test

Secondary outcomes

Secondary outcome: physiology

Time frame: 3 time points: antepatum, immediate postpartum, 6 weeks post partum

A small sub-cohort of women will undergo an additional 2 hour fasting 75g OGTT in the third trimester with measurements of insulin, cytokines, lipids.

Sponsors and collaborators

Lead sponsor

MetroHealth Medical Center

Other

Collaborators

Centers for Disease Control and Prevention
Loyola University

Registry information

Important dates

Study start: 2012
Primary completion: 2016
Study completion: 2019
First posted: Mar 10, 2014
Registry last updated: Feb 25, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed