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OpenTrials
Completed

NCT Number: NCT05210556

Oral Antibiotic Bowel Preparation in Gynecologic Oncology Surgery

The purpose of this study is to investigate whether the use of a preoperative antibiotic bowel regimen is associated with a reduced risk of deep organ/space surgical site infection in gynecologic oncology surgery.

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Key information

Conditions

Surgical Site Infection Gynecologic Cancer Infections Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Surgical Complication Surgical Wound Infection Wound Infection

Age range

18 year–99 year

Sex eligibility

Female

Study type

Observational

Primary location

WellSpan

York, Pennsylvania, 17403, United States

About this study

This is a retrospective chart review study. Patients who underwent scheduled intra-abdominal surgery with a WellSpan gynecologic oncologist will be identified and their chart reviewed for demographic data of age, race, BMI, comorbidities, and type of surgery. Those patients who had a deep organ/space surgical site infection within 30 days postoperatively will be identified. The numbers of these infections before and after August 2020, at which time all patients moving forwards were prescribed antibiotic bowel preparation, will then be statistically analyzed and compared to see if the institution of the antibiotic bowel preparation was associated with a reduction in surgical site infection.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Underwent scheduled intra-abdominal surgery with a WellSpan gynecologic oncologist

Exclusion criteria

  • Unscheduled surgery
  • Intraoperative consult by a WellSpan gynecologic oncologist

Treatment and study plan

Diagnosed with Surgical Site Infection

Other

As an observational study, this notates patients who were diagnosed with a deep organ/space surgical site infection within 30 days of surgery

Primary outcomes

  1. Surgical Site Infection Rates Associated with Antibiotic Bowel Prep

    Time frame: 2019-2021

    Rate of surgical site infection rate as associated with or without use of antibiotic bowel preparation

Sponsors and collaborators

Lead sponsor

WellSpan Health

Other

Registry information

Important dates

Study start
2021
Primary completion
2022
Study completion
2024
First posted
Jan 27, 2022
Registry last updated
Mar 28, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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