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Completed

NCT Number: NCT07712991

ORAL AND INTRA - LIGAMENTARY PIROXICAM for Post Endodontic Pain Management

the study find out the effect of oral and intra ligamentary piroxicam on the post endodontic pain . it tell us which one is better among both methods of using piroxicam

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Key information

Conditions

Pain Management Agnosia Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Perceptual Disorders Post Endodontic Pain Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Pakistan Institute of Medical Sciences

Islamabad, Pakistan

About this study

post endodontic pain is very common and it effect the quality of life of patients. piroxicam reduces the perception of pain . it is usually prescribe as oral medication but out study evaluate the effect of intra-ligamentary use of piroxicam to reduce post procedure pain.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient diagnosed with irreversible pulpitis
  • Patient have Tooth pain before Root canal treatment

Exclusion criteria

  • Patient already treated with root canal
  • Necrotic Tooth

Treatment and study plan

intra-ligamentary

Other

intra ligamentary mode of piroxicam use

Primary outcomes

  1. pain intensity

    Time frame: 12, 24,48 hours

    Pain intensity will be measured by Visual Analogue scale(VAS). Patient will advised to rate there pain intensity from 0 to 10 after 12 hours, 24 and 48 hours. So both groups patient will record there pain in number and report to dentist in follow-up visit.

Sponsors and collaborators

Lead sponsor

Pakistan Institute of Medical Sciences

Other Gov

Registry information

Official study title

Effect of ORAL AND INTRA - LIGAMENTARY PIROXICAM for Post Endodontic Pain Management

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Jul 20, 2026
Registry last updated
Jul 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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