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NCT Number: NCT07009652

Optimization of Transport and Use of a Mobile ECMO Team in Patients With Sudden Cardiac Arrest in the Moravian-Silesian Region

This study evaluates the feasibility of implementing a mobile extracorporeal membrane oxygenation (ECMO) team and optimizing patient transport logistics.

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Key information

Conditions

Cardiac Arrest With Successful Resuscitation Cardiac Arrest, Cause Unspecified Cardiovascular Diseases Heart Arrest Heart Diseases Out-of-Hospital Cardiac Arrest

Age range

3 year–60 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Emergency Medial Services, Moravian-Silesian Region, Ostrava, Moravian-Silesian Region, Czechia

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About this study

The aim of the study is to improve neurological outcomes in out-of-hospital cardiac arrest (OHCA) cases in the Moravian-Silesian Region. By analysing regional epidemiological and demographic data, the project aims to identify key factors for reducing the time from collapse to the initiation of ECMO and to support the development of effective protocols for extracorporeal cardiopulmonary resuscitation (ECPR).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • out-of-hospital cardiac arrest
  • indication for ECPR

Exclusion criteria

  • death at the scene of the accident
  • withdrawal of the informed consent

Treatment and study plan

Extracorporeal cardiopulmonary resuscitation (ECPR)

Procedure

Extracorporeal cardiopulmonary resuscitation (commonly known as ECPR) is a method of cardiopulmonary resuscitation (CPR) that passes the patient's blood through a machine in a process to oxygenate the blood supply.

Primary outcomes

  1. Neurological outcome after 30 days (CPC score)

    Time frame: 30 days

    Assessment of the neurological status of patients 30 days after the event using the Cerebral Performance Category (CPC) scale, which measures the extent of neurological impairment:

    • CPC 1 = good neurological condition
    • CPC 2 = mild impairment
    • CPC 3-5 = serious impairment, vegetative state or death The primary endpoint of the study is the proportion of patients with a favourable neurological outcome (CPC 1-2).

Secondary outcomes

  1. Time from collapse to initiation of ECMO

    Time frame: Up to 2 hours

    Measuring the time (in minutes) from patient collapse to ECMO initiation. The aim is to analyse how this time affects neurological outcome.

  2. Transport time to the ECMO centre

    Time frame: Up to 2 hours

    Measurement of the time (in minutes) from the arrival of the Emergency Medical Services (EMS) at the scene to the admission of the patient to the ECMO centre.

  3. Arrival time for the mobile ECMO team to the scene

    Time frame: Up to 2 hours

    Time interval (in minutes) from activation of the mobile ECMO team to its arrival at the scene. The aim is to evaluate the effectiveness of the model and the potential time benefit of intervention in the field.

Study contacts

Contact information is provided by the study sponsor or research team.

Jiří Hynčica

CONTACT

[email protected]

0042059737 ext. 2587

Sponsors and collaborators

Lead sponsor

University Hospital Ostrava

Other

Collaborators

  • Emergency Medical Services, Moravian-Silesian Region

Registry information

Official study title

Proposal for the Organisation of the Procedure for Extracorporeal Cardiopulmonary Resuscitation of Patients With Sudden Cardiac Arrest in the Pre-hospital Environment of the Moravian-Silesian Region

Important dates

Study start
2025
Primary completion
2026
Study completion
2028
First posted
Jun 6, 2025
Registry last updated
Jun 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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