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Completed

NCT Number: NCT01263522

Optimization of Preventive Effects of Physical Training

Health-promoting effects of physical exercise are well-investigated especially for endurance activities. However, for different individuals, positive effects have different sizes, even non-responders are observed. Other forms of training, such as strength training and interval training, are less well investigated. Therefore, a comparative longitudinal training study is warranted to examine differences of preventive effects (outcome measures: ergometric descriptors of physical performance, established risk factors and prognostic factors for cardiovascular diseases) of continuous endurance training, interval training and strength endurance training.

In a second stage, the observed non-responders will perform a different type of training (cross-over). It is expected, that besides a comparative general efficacy evaluation of the three training types, improved recommendations for optimized individualization of training parameters can be formulated.

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Key information

Age range

30 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Institute of Sports and Preventive Medicine, Saarland University, Bldg. B 8-2, 66123 Saarbrücken

Saarbrücken, Saarland, 66123, Germany

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • untrained
  • healthy
  • non-smoking

Exclusion criteria

  • Contraindications for physical activity
  • BMI > 30 kg/m2
  • resting blood pressure > 160/100 mmHg
  • diabetes
  • total cholesterol > 300 mg/dl
  • maximal oxygen uptake > 50 ml/min/kg for men and > 45 ml/min/kg for women respectively
  • other complaints or diseases that might interfere with exercise training

Treatment and study plan

different training programs

Other

two different endurance programs and one strength endurance program

Control condition

Other

unchanged lifestyle

Primary outcomes

  1. VO2 max

    Time frame: 6 months

    determined during treadmill testing

Secondary outcomes

  1. resting heart rate

    Time frame: 6 months

  2. resting blood pressure

    Time frame: 6 months

  3. blood lipid profile

    Time frame: 6 months

    ratio: total cholesterol/HDL-cholesterol

Sponsors and collaborators

Lead sponsor

Universität des Saarlandes

Other

Registry information

Official study title

Optimization of Preventive Effects of Physical Training "Saarländische Ausdauer-Etappe (SAusE)"

Acronym: SAusE

Important dates

Study start
2010
Primary completion
2013
Study completion
2013
First posted
Dec 20, 2010
Registry last updated
May 11, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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