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OpenTrials
Active, Not Recruiting

NCT Number: NCT06627933

Optimization of Management in Patients With Cardiovascular Disease After Lower Limb Joint Replacement

The goal of the study is to evaluate the frequency of cardiovascular and thromboembolic complications in patients with cardiovascular disease after lower limb joint replacement, the influence of known risk factors and strategies for perioperative prevention of thromboembolic complications on the frequency of cardiovascular complications and to develop approaches to optimize antithrombotic prevention tactics.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Thromboembolism Anticoagulant-induced Bleeding Cardiovascular Diseases Embolism and Thrombosis Vascular Diseases Venous Thromboembolism

Age range

18 year–95 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University Hospital #1

Moscow, 119991, Russia

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Informed consent
  • Age older than 18 y.o.
  • Cardiovascular disease
  • Indications for planned lower limb joint replacement surgery

Exclusion criteria

  • Pregnancy
  • Psychiatric disorders
  • Decompensated heart failure or acute heart failure
  • Known diagnosis of cancer

Treatment and study plan

No intervention

Other

No intervention

Primary outcomes

  1. Bleeding

    Time frame: 1 month

    All the cases of major and minor bleeding within 1 month

  2. Bleeding

    Time frame: 3 months

    All the cases of major and minor bleeding within 3 months

  3. Bleeding

    Time frame: 6 months

    All the cases of major and minor bleeding within 6 months

  4. Thromboembolism

    Time frame: 1 month

    All the cases of venous thromboembolism within 1 month

  5. Thromboembolism

    Time frame: 3 months

    All the cases of venous thromboembolism within 3 months

  6. Thromboembolism

    Time frame: 6 months

    All the cases of venous thromboembolism within 6 months

Sponsors and collaborators

Lead sponsor

I.M. Sechenov First Moscow State Medical University

Other

Registry information

Important dates

Study start
2023
Primary completion
2025
Study completion
2027
First posted
Oct 4, 2024
Registry last updated
May 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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