Beijing Tongren Hospital
Beijing, Beijing Municipality, China
NCT Number: NCT05397158
Older adults are susceptible to intestinal tumors. Colonoscopy can screen colorectal cancer, adenoma and other diseases. There is a large demand for colonoscopy in the older adults, and the risk during peri-colonoscopy period is high. According to the common intestinal preparation methods and the characteristics of the older adults, the investigators propose a modified method, that is single administration of low dose polyethylene glycol (PEG). Specifically, take 30ml lactulose in the morning 1 day before the examination, and eat without residue in lunch and dinner, Take 2L PEG in the morning of the examination day and fast at breakfast and lunch of the day. Taking 4L PEG in 2 days as the control group. The fasting and diarrhea period is shorter in the modified group than that in the control group, and the dose of PEG is less. Lactulose, a laxative, is taken one day before the examination, and the intestinal preparation time is longer than that of single administration. The situation of comfort, sleep and fecal incontinence during the intestinal preparation of the two groups will be compared. The results of electrolyte, blood glucose and B-type brain natriuretic peptide between the two groups will be also compared. The effect of intestinal preparation will be evaluated by the standardization of Boston intestinal preparation scale, and endoscopist blind method will be used in colonoscopy.
Looking for future studies?
Notify Me50 year and older
All sexes
Interventional
Not applicable
Beijing, Beijing Municipality, China
The participants in control group take 2L PEG the day before the examination, fast at dinner (participants without diabetes) and eat without residue (participants with diabetes). Participants take 2L PEG again in the morning of the examination day, and fasted at breakfast and lunch of the day.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Patients in single administration of low dose polyethylene glycol (PEG) group: Take 30ml lactulose and 2L PEG.
Patients in control group: Take 4L PEG.
Time frame: Up to 1 hour
The effect of intestinal preparation will be evaluated by Boston Intestinal Preparation Scale.The minimum score is 0,and the maximum score is 9. Higher scores mean a better outcome. Endoscopist blind method will be used.
Time frame: Up to 1 week
Blood potassium in mmol/L.
Time frame: Up to 1 week
Blood sodium in mmol/L.
Time frame: Up to 1 week
Blood glucose in mmol/L.
Time frame: Up to 1 week
BNP in pg/ml.
Time frame: Two days
Comfort situation questionnaire. The score of comfort questionnaire is 1 to 10, 1 represents extremely uncomfortable and 10 represents very comfortable.
Time frame: One day
Sleep situation questionnaire. The length of sleep in hour, the number of awakening, the number of urination and defecation.
Time frame: One day
Fecal incontinence questionnaire. Does the patient have fecal incontinence and the number of fecal incontinence.
Beijing Tongren Hospital
Other
Study on Optimization of Intestinal Preparation Before Colonoscopy in Older Patients
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06763705
Colonoscopy, Conscious Sedation
Unaizah, Al-Qassim Region, Saudi Arabia
View Trial DetailsNCT06407531
Colonoscopy
Antalya, Finike, Turkey (Türkiye)
View Trial DetailsNCT04921488
Colonic Diseases, Colonoscopy
Angers, France
View Trial DetailsNCT07590869
Anxiety, Anxiety Disorders
Malatya, Turkey (Türkiye)
View Trial Details