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Completed

NCT Number: NCT02411864

Optimal Low B-value in Intravoxel Incoherent Motion Diffusion-weighted MR Imaging of the Brain

Our research aims to reveal whether the low b-values distribution and the number of NEX for each b value will influence the accuracy of pseudodiffusion parameter derived from IVIM in brain.

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Key information

Conditions

Healthy Volunteers

Age range

25 year–35 year

Sex eligibility

Male

Study type

Observational

About this study

As an improved MRI technique, diffusion-weighted imaging (DWI) is considered the most sensitive for early pathological changes. Perfusion measurement has been shown to improve sensitivity and predictive value for tumor grading and prognosis, also as a predicator of recovery with reperfusion in patients of acute ischemic stroke.Our research aims to reveal whether the low b-values distribution and the number of NEX for each b value will influence the accuracy of pseudodiffusion parameter derived from IVIM in brain.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • no hypertension or cerebral vascular diseases,
  • no systemic metabolic disease;
  • no infection or fever;
  • no use of corticosteroid drugs;
  • no MRI contraindication.

Exclusion criteria

Treatment and study plan

different low b-values distribution

Other

Primary outcomes

  1. Parameters D* and f in healthy white matter or gray mater

    Time frame: 2-3 days

Sponsors and collaborators

Lead sponsor

Tang-Du Hospital

Other

Registry information

Official study title

Can the Distribution of Low B-value and the NEX Influence the Pseudodiffusion Parameter Derived From IVIM in Brain?

Important dates

Study start
2014
Primary completion
2014
Study completion
2014
First posted
Apr 8, 2015
Registry last updated
Jul 5, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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