University Malaya Medical Centre
Kuala Lumpur, 59100, Malaysia
NCT Number: NCT01371968
This study aims to determine the optimal dose of alfentanil in suppressing the airway reflexes during supreme LMA removal in anaesthetized adult.
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Notify Me18 year–49 year
All sexes
Interventional
Not applicable
Kuala Lumpur, 59100, Malaysia
The removal of LMA may be associated with coughing, biting, agitation and airway complication such as laryngospasm. Thus it is advisable to remove the LMA when the patient is breathing spontaneously and when the airway reflexes are still depressed. A number of techniques have been used to prevent this adverse emergence phenomenon, such as removing the tube while the patient is in deep plane of anaesthesia or administration of local anaesthetic and intravenous opioids
The administration of intravenous opioids before emergence may be useful for preventing cough, agitation and hemodynamic response. Alfentanyl is proven to suppress cough and agitation during the endotracheal tube emergence. However, its use in suppressing cough in LMA patient has not been evaluated.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Alfentanil is administered intravenously at the end of surgery.
Other names: Rapifen
Time frame: 6 months
Time frame: after administration of alfentanil and within 1 min of LMA removal
University of Malaya
Other
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