Optical Coherence Tomography (OCT) in Retinal Vasculitis

Inclusion criteria

• Diagnosis of retinal vasculitis

Exclusion criteria

• Inability to give informed consent.
• Inability to complete the qualifying study tests within a 30 day period from date of enrollment
• Significant renal disease, defined as a history of chronic renal failure requiring dialysis or kidney transplant.
• A prior history of reaction to fluorescein or other dyes.
• A condition that, in the opinion of the investigator, would preclude participation in the study (e.g. unstable medical status including blood pressure, cardiovascular disease, and glycemic control).
• Blood pressure > 180/110 (systolic above 180 OR diastolic above 110). If blood pressure is brought below 180/110 by anti-hypertensive treatment, subject can become eligible.
• Systemic anti-vascular endothelial growth factor (VEGF) or pro-VEGF treatment within 4 months prior to treatment.
• Women of child-bearing potential: pregnant or lactating or intending to become pregnant within the next 12 months due to unknown safety of fluorescein angiography.
• Prior panretinal photocoagulation (PRP) or focal laser that would alter the macular perfusion and retinovascular features.
• Inability to maintain stable fixation for OCT imaging.
• Other ocular condition is present such that, in the opinion of the investigator, may alter the retinal perfusion.
• An ocular condition is present that, in the opinion of the investigator, might affect or alter visual acuity during the course of the study (i.e. cataract)
• Substantial cataract that, in the opinion of the investigator, is likely to decrease visual acuity by 3 lines or more (i.e. cataract would be reducing acuity to 20/40 or worse if the eye was otherwise normal).
• Media opacity or otherwise that would prevent either fixation or ability to obtain adequate images as determined by the examiner.
• History of major ocular surgery (including vitrectomy, cataract extraction, scleral buckle, any intraocular surgery, etc) within prior 4 months.