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OpenTrials
Completed

NCT Number: NCT01361828

Optic Nerve and Retinal Functions With Bevacizumab

The purpose of this study is to investigate the possible affection of optic nerve and retinal functions following intravitreal bevacizumab injection in human eyes.

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Key information

Conditions

Choroidal Neovascular Membrane

Age range

24 year–62 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Cairo University

Cairo, --- Select One ---, 11421, Egypt

About this study

To evaluate the retinal and optic nerve functions of bevacizumab when injected intravitreal in human eyes using electrophysiological tests; Electroretinogram (ERG) and Visual Evoked Potentials (VEP). Forty five eyes of 45 patients with choroidal neovascular membrane (CNV) who were prepared for intravitreal injections of 1.25mg bevacizumab underwent baseline ERG and VEP in both eyes before, and at 1 and 4 weeks after the intravitreal injections.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • CNV

Exclusion criteria

  • Previous Intravitreal Injections

Treatment and study plan

electrophysiology

Procedure

Visual Evoked Potential and Elctroretinogram

Primary outcomes

  1. Visual Evoked Potential and Electroretinogram

    Time frame: 4 weeks

    VEP and ERG baseline and at 1 and 4 weeks post intravitreal injection of bevacizumab.

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Electrophysiological Assessment of Optic Nerve and Retinal Functions Following Intravitreal Injection of Bevacizumab (Avastin).

Important dates

Study start
2010
Primary completion
2010
Study completion
2010
First posted
May 27, 2011
Registry last updated
May 27, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.