Skip to main content
OpenTrials
Completed

NCT Number: NCT03628846

Opioid Use After Traumatic Injury in Adolescents

Currently, 1 in 8 adolescents continue to receive prescription opioids a year or more after injury. By longitudinally surveying patients, we can identify risk factors and pathways to nonmedical opioid use. Furthermore, by assessing whether pain management and mental health treatment after injury moderates sustained opioid use and prescription opioid misuse, we can create targeted interventions to reduce future nonmedical opioid use in adolescents.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Opioid Use Adolescent Behavior Behavior Chemically-Induced Disorders Mental Disorders Substance Abuse Disorder Substance-Related Disorders Traumatic Injury Wounds and Injuries

Age range

12 year–20 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Indiana University

Indianapolis, Indiana, 46202, United States

About this study

This is a prospective cohort study that will follow participants for 2 years and administer surveys to adolescents both traumatically injured and uninjured on prescription opioid usage, substance use, utilization of pain management and mental health services, and mental and physical health condition conditions.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient is 12-20 years of age
  • Adolescent admitted for trauma OR adolescent with no recent trauma
  • English speaking
  • Consent can be obtained from a parent or guardian

Exclusion criteria

  • Patients with severe brain injuries or other injuries that prevent survey participation

Treatment and study plan

Primary outcomes

  1. Prospectively determine drivers of sustained opioid use and prescription opioid misuse.

    Time frame: 2 years

Secondary outcomes

  1. Identify patient-reported factors for sustained prescription opioid use, including chronic pain and mental health conditions such as PTSD, depression, anxiety, and sleep disorders.

    Time frame: 2 years

  2. Assess behavioral, social, and clinical predictors of prescription opioid misuse and nonmedical opioid use by longitudinally surveying injured adolescents.

    Time frame: 2 years

  3. Qualitatively determine patients' motives for continued opioid therapy, prescription opioid misuse, and nonmedical opioid use by interviewing injured adolescents.

    Time frame: 2 years

  4. Analyze genetic information, obtained via saliva sample and the company 23andMe, from each participant to determine if some people are more likely to use more pain medication than others or respond better to certain pain medications.

    Time frame: 2 years

Sponsors and collaborators

Lead sponsor

Indiana University

Other

Registry information

Official study title

A Prospective Survey of Opioid Use After Traumatic Injury in Adolescents

Important dates

Study start
2018
Primary completion
2023
Study completion
2023
First posted
Aug 14, 2018
Registry last updated
May 19, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.