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OpenTrials
Completed

NCT Number: NCT06835335

Opioid Prescribing in the Emergency Department for Sickle Cell Disease

This study consists of a clinical vignette presented to emergency physicians asking them what they would prescribe to a patient with acute abdominal pain.

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Key information

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Being a emergency physician

Exclusion criteria

  • Working outside of Europe.

Treatment and study plan

opioid prescription

Behavioral

The intervention consisted of a randomized questionnaire presenting a clinical case of a patient suffering from severe abdominal pain. The control case was "As an emergency physician in an adult emergency department, you are presented with the following patient: The patient is a 39-year-old non-smoking male/female with a history of Meniere's disease and an allergy to Bactrim. He/she presents with abdominal pain that began abruptly 2 hours ago and has persisted despite taking NEFOPAM 45 minutes ago. This is his first episode. His/her vital signs are blood pressure 140/66, heart rate 91, pulse ox 97%, temperature 36.8°C. He/she rates his/her pain as 8/10 without any analgesic position. On clinical examination he/she presents with localized epigastric tenderness. The rest of the abdomen is soft, painless and depressed. There are hydro-aeriform noises. No diarrhea or vomiting. The rest of the clinical examination showed no abnormalities.". In the intervention case, patient had history of S

Primary outcomes

  1. Morphine prescription

    Time frame: through study completion, an average of 1 year

    The proportion of patient for which physician would have prescribed morphine

Secondary outcomes

  1. Analgesic prescription between groups

    Time frame: through study completion, an average of 1 year

    To compare analgesic prescription between groups

  2. factors associated with differences in management between groups

    Time frame: through study completion, an average of 1 year

    identify factors associated with differences in management (urgency level, morphine prescription and computed tomography scan ordering)

  3. Differences according to patient and practitioner gender

    Time frame: through study completion, an average of 1 year

    analyze the difference in morphine treatment prescribed according to patient and practitioner gender

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Nīmes

Other

Registry information

Official study title

Differential Opioid Prescribing in the Emergency Department for Patients With Sickle Cell Disease: a Vignette-based International Randomised Trial.

Acronym: DOPED-SCD

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Feb 19, 2025
Registry last updated
Jan 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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