Open Radical Prostatectomy Versus Curative Radiotherapy for Treatment of Organ Confined Prostate Cancer (Retrospective Comparative Study)

In the last few decades not only the diagnosis but also the treatment options for prostate cancer have changed significantly. During this time the surgical procedure of open radical prostatectomy was substantially modified(1,2) and is nowadays considered a safe procedure providing high cancer control rates with low morbidity.(3) The main goal of radical prostatectomy regardless of the approach remains the eradication of cancer while preserving pelvic organ function,whenever possible.(4)

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Key information

Conditions

Prostate Cancer Genital Diseases Genital Diseases, Male Genital Neoplasms, Male Male Urogenital Diseases Neoplasms Neoplasms by Site Prostatic Diseases Prostatic Neoplasms Urogenital Diseases Urogenital Neoplasms

Age range

40 year and older

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Sohag University

Sohag, 82511, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Cancer prostate: confirmed by prostate biopsy Cancer stage: T2,T3

Exclusion criteria

coagulopathy. Pulmonary diseases metastatic tumor

Treatment and study plan

open radical prostatectomy

Procedure

open surgery to remove prostate gland and the tumor

Curative radiotherapy

Radiation

radiotherapy to the prostate gland and the tumor

Primary outcomes

tumor control

Time frame: 6 months

percentage of tumor recurrence

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Important dates

Study start: 2022
Primary completion: 2026
Study completion: 2027
First posted: Oct 3, 2025
Registry last updated: Apr 7, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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