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Completed

NCT Number: NCT00212953

OPALS Critical Care Sub-Studies

The purpose of the study is to evaluate the incremental benefit of a full advanced life support EMS program on the outcomes of chest pain, respiratory and major trauma patients.

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Key information

Conditions

Cardiac Arrest Cardiovascular Diseases Chest Pain Dyspnea Heart Arrest Heart Diseases Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Respiration Disorders Respiratory Tract Diseases Signs and Symptoms Signs and Symptoms, Respiratory Wounds and Injuries

Age range

16 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Cambridge Base Hospital, Cambridge, Ontario, Canada

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Chest Pain Sub-Study: Adult patients with a complaint of chest pain of an acute nature transported to hospital by ambulance. Patients with a complaint of pain in arms, neck or jaw if consistent with myocardial ischemia. Patients must have an ambulance return code of prompt, urgent, or no patient carried.
  • Respiratory Sub-Study: Adult patients with a chief complaint of shortness of breath defined as ACR codes of Respiratory Failure, Shortness of Breath NYD, Pulmonary Edema (CHF), Asthma and had either prehospital assisted ventilation or abnormal respiratory rates (>=24 or <=10)
  • Major Trauma Sub-Study: Adult patients who have suffered an injury from any mechanism with an Injury Severity Score of >12 who have been transported to hospital by land ambulance, and who have been entered into the Ontario Trauma Registry (OTR) Comprehensive Data Set.

Exclusion criteria

  • All Sub-Studies:
  • Patients under the age of 16
  • Patients who are vital signs absent prior to EMS arrival.
  • Chest Pain Sub-Study:
  • Patients suffering primarily from respiratory distress, respiratory failure, pulmonary edema, asthma, palpitations or epigastric pain. pain

Treatment and study plan

Advanced Life Support

Procedure

Primary outcomes

  1. Survival to discharge

Secondary outcomes

  1. Generic Quality of Life

  2. Disease Specific Quality of Life CPC Score and FIM Score

  3. Performance of ALS Procedures

  4. Response Time Intervals

  5. Length of Stay in Hospital

  6. Length of Stay in Critical Care Units

  7. Ventilator time

  8. Disease Specific Quality of Life

Sponsors and collaborators

Lead sponsor

Ottawa Hospital Research Institute

Other

Collaborators

  • Ontario Ministry of Health and Long Term Care

Registry information

Official study title

Ontario Prehospital Advanced Life Support (OPALS) Study Phase III Cardiac Arrest and Critical Care Sub-Studies - Chest Pain Sub-Study, Respiratory Sub-Study, and Major Trauma Sub-Study

Important dates

Study start
1997
Study completion
1999
First posted
Sep 21, 2005
Registry last updated
Oct 15, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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