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Completed

NCT Number: NCT03678571

Oocyte Vitrification Aided With Latrunculin A

Using cytoskeleton Stabilizer the Latrunculin A would improve the outcome of oocyte vitrification

Completed

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Key information

Conditions

Infertility Genital Diseases Urogenital Diseases

Age range

18 year–42 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Qena Fertility Center, Qina, Qena Governorate, Egypt

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Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • indication for oocyte cryopreservation

Exclusion criteria

-

Treatment and study plan

Latrunculin A supplemented vitrification medium

Other

Vitrification of human oocyte in medium supplemented with Latrunculin A

Primary outcomes

  1. survival after thawing

    Time frame: 6 days after thawing

Secondary outcomes

  1. fertilization rate

    Time frame: 6 days of culture

  2. Rates of blastocyst formation and quality

    Time frame: 6 days of culture

    Number of formed blastocyst and high-quality blastocysts per fertilized oocytes

  3. embryo utilization rate

    Time frame: 6 days of culture

    Number of utilized embryos per fertilized oocytes

  4. clinical pregnancy rate

    Time frame: three months

    Number of pregnant women with fetal pulsation per recruited cycles

  5. ongoing pregnancy rate

    Time frame: 12 months

Sponsors and collaborators

Lead sponsor

Ibn Sina Hospital

Other Gov

Collaborators

  • Banoon IVF Center

Registry information

Official study title

Latrunculin A for Oocyte Vitrification

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
Sep 19, 2018
Registry last updated
Jul 16, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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