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Completed

NCT Number: NCT06084741

Omitting Drains After Repair of Peptic Ulcer Perforations

. This study aimed to evaluate ERAS application outcomes via omitting the intraabdominal drains compared to regular using of the drains in patients undergoing perforated duodenal ulcer repairs in emergency abdominal surgeries.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Cairo University

Cairo, 11511, Egypt

About this study

Patients will be randomly assigned into two groups. In Group A : the investigators will put intraabdominal drains, and in Group ,thd investigators will not put any intraabdominal drains. Our primary outcomes will be hospital stayl engthand pain score;Data analysis packages will be SPSS version 21 Qualitative data will be presented by number and percentage, quantitative data by mean, standard deviation, median and interquartile range.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients older than 18 years with perforated peptic ulcer who underwent exploratory laparotomy or laparoscopy and repair with omental pedicle techniques will included in the study.

Exclusion criteria

  • preoperative shock on admission.
  • Delayed presentation more than 24 hours.
  • known malignant gastric ulcers confirmed by histopathology.
  • the presence of neuropsychiatric disease, pregnant and lactating women.
  • predisposing factors for impaired wound healing (e.g., currently using immunosuppressive agents, or chronic use of steroids), the presence of HIV/AIDS.
  • Intraoperative findings consistent with malignant ulcers. • American Society of Anesthesiologists grade III/IV, or had an alternative perioperative diagnosis. • Ulcer size more than 2 cm in diameter.

Treatment and study plan

Omitting of usage of intraabdominal drains after repair of peptic ulcer perforations

Other

omitting the intraabdominal drains

Using intraabdominal drains

Other

The investigators will put intraabdominal drains

Primary outcomes

  1. number of days of hospital stay

    Time frame: Up to 30 days

    hospital stay length

  2. number of patients with infection-related postoperative complications such as superficial, deep or organ space SSI, hospital acquired pneumonia

    Time frame: 30 days

    number of patients with infection-related postoperative complications such as superficial, deep or organ space SSI, hospital acquired pneumonia

  3. incidence of Post operative repair leak

    Time frame: 30 days

    incidence of Post operative repair leak

Secondary outcomes

  1. number of days before frist bowel motion

    Time frame: 7 days

    number of days before frist bowel motion

  2. severity of operative pain measured by Visual Analogue Scale (VAS

    Time frame: 7 days

    from 1 to 10 1 indicated minimum pain and 10 maximum pain

  3. INCIDENCE OF postoperative nausea and vomiting (PONAV

    Time frame: 7 days

    INCIDENCE OF postoperative nausea and vomiting (PONAV

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Omitting of Usage of Intraabdominal Drains After Repair of Peptic Ulcer Perforations Compared to Traditional Use of Drains; Comparative Study

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Oct 16, 2023
Registry last updated
Aug 26, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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