Omega-3-Polyunsaturated Fatty-Acids (N3-Pufa) In Patients With Severe Chronic Heart Failure

To investigate whether n3-fatty acids have beneficial effects in chronic heart failure as regards circulatory function.

Completed

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Key information

Conditions

Chronic Heart Failure

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2 / Phase 3

Primary location

Medical University of Vienna

Vienna, A-1090, Austria

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Chronic heart failure of non-ischemic origin
Age ≥18 years
NYHA functional class III-IV
LVEF < 35 %
Optimized heart failure therapy
plasma NT-BNP >2000pg/ml

Exclusion criteria

Current treatment with Omacor or other fish oil products
Known hypersensitivity to the study drug
Ischemic cardiomyopathy
Uncorrected significant valvular heart disease
Heart failure due to congenital heart disease
Restrictive cardiomyopathy
Alcoholic heart disease
Acute myocarditis
Continuous i.v. therapy for heart failure
Mechanical assist device
Life expectancy <1 year due to non-cardiac causes
Inability to perform bicycle testing
Women of childbearing potential not practicing a save contraception method
Current participation in another intervention study
Participation in another study with an intervention within the last 3 months.

Treatment and study plan

Omacor

Dietary Supplement

Sponsors and collaborators

Lead sponsor

Medical University of Vienna

Other

Registry information

Official study title

Omega-3-Polyunsaturated Fatty-Acids (N3-Pufa) In Patients With Severe Chronic Heart Failure:Effects On Endothelial Function, Left Ventricular Remodelling, Natriuretic Peptide Levels, And Exercise Capacity

Important dates

Study start: 2005
Primary completion: 2008
Study completion: 2008
First posted: Sep 8, 2005
Registry last updated: Jul 13, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed