Omega-3 Fatty Acid and Colorectal Adenoma

Patients aged >40 years who underwent elective colonoscopies were recruited from ten institutions. Patients with a history of colorectal cancer or long-term dietary interventions were excluded. Participants completed a food frequency questionnaire (FFQ) prior to endoscopy. FFQ data were analyzed using energy-, age-, sex-, and body mass index-adjusted models; the dietary supplemental omega-3 intake was analyzed separately. Colonoscopy outcome data, including the adenoma number, pathology, and location, were collected. Participants were stratified into omega-3 consumption quartiles to assess colorectal adenoma incidence trends using P for trend analysis.

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Key information

Conditions

Colorectal Neoplasms Adenoma Colon Colonic Diseases Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site Rectal Diseases

Age range

40 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Dongguk University Ilsan Hospital

Goyang-si, Gyeonggi Province, 14353, South Korea

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

all patients aged more than 40 years of age, scheduled for elective colonoscopy.

Exclusion criteria

inflammatory bowel diseases
history of colorectal neoplasms
prior gastrointestinal surgery
substance abuse including alcohol
an inability to complete the survey due to emergency endoscopy
cognitive impairments and those undergoing significant dietary modifications

Treatment and study plan

Dietary intake of omega-3 fatty acid

Dietary Supplement

Participants were stratified into omega-3 consumption quartiles to assess colorectal adenoma incidence trends

Primary outcomes

Incidence of Colorectal adenoma

Time frame: at the completion of the colonoscopy procedure

among groups with different omega-3 intake levels

Sponsors and collaborators

Lead sponsor

DongGuk University

Other

Registry information

Official study title

Omega-3 Fatty Acid Intake and Risk of Colorectal Adenoma

Important dates

Study start: 2021
Primary completion: 2023
Study completion: 2024
First posted: May 23, 2024
Registry last updated: May 24, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed