Oligodendrocyte Progenitor Cell Culture From Human Brain

Recent developments in the understanding of stem- and progenitor cell differentiation raises hopes that brain damage in chronic neurological diseases may become repaired by systemic or focal transplantation of such cells. Clinical trials of stem- or progenitor cell transplantation in multiple sclerosis are currently premature. The researchers developed a protocol for human oligodendrocyte progenitor cell culture from human brain for the treatment of demyelinating disease.

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Key information

Conditions

Demyelinating Diseases Nervous System Diseases

Age range

20 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

Assistant Professor Subsai Kongsaengdao

Bangkok, 10400, Thailand

About this study

Oligodendrocyte progenitor cell line were cultures and will be transplanted into the patient with Multiple sclerosis.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Male or female 20-65 years of age
Informed consent
Has elective craniotomy surgery

Exclusion criteria

HIV, hepatitis, and other central nervous system (CNS) infections
Dementia, Alzheimer disease, and neurodegenerative disease

Treatment and study plan

Oligodendrocyte progenitor cell culture/craniotomy

Procedure

Oligodendrocyte progenitor cell culture protocol of Rajavithi Hospital will be apply

Other names: Rajavithi Oligodendrocyte progenitor cell culture protocol

Primary outcomes

Number of oligodendrocyte progenitor cell differentiation

Time frame: one month

Sponsors and collaborators

Lead sponsor

Department of Medical Services Ministry of Public Health of Thailand

Other Gov

Registry information

Official study title

Phase 1: Oligodendrocyte Progenitor Cell Culture From Human Brain

Important dates

Study start: 2007
Primary completion: 2010
Study completion: 2010
First posted: Jan 27, 2006
Registry last updated: Oct 19, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed