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Completed

NCT Number: NCT06522178

Oldest-old Patients Anesthesia in Orthopedic Surgeries

Average life span, life expectancy, and the number of older people, aged 65 years and over, have increased during the last decades. As life expectancy increased, the rate of emergency and elective surgical interventions has also increased in the older age group. Although good health is required to reach an advanced age, over time, organ functions may deteriorate, and some challenges may develop that will negatively affect the balance of homeostasis. Stress, such as trauma or surgery, can cause deterioration in organ functions or aggravation of impaired functions. The risk of developing undesirable events is higher, due to the diminished reserve and function, during anesthesia applied to these patients. There is a limited number of studies in the literature about the relation between the anesthesia technique and morbidity and mortality in oldest old patients operated for orthopedic surgery. In this study, we aimed to analyze the data of the oldest-old patients operated on for orthopedic surgery between 2016-2022, retrospectively, and to investigate the relationship between anesthesia technique and adverse effects including morbidity and mortality.

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Key information

Conditions

Age range

80 year–100 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Istanbul Medeniyet University

Istanbul, 34730, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged 80 years and above
  • Underwent orthopedic surgery

Exclusion criteria

  • Those who had the operation with local anesthesia

Treatment and study plan

Patient' ages

Other

Patients were divided into two groups according to their ages.

Primary outcomes

  1. Mortality

    Time frame: one month after operation

    postoperative mortality

  2. Anesthesia Techniques

    Time frame: up to 6 hours

    Data were also analyzed and compared with groups and between groups according to the applied anesthesia technique (general anesthesia versus regional anesthesia).

  3. Type of operation

    Time frame: up to 6 hours

    Orthopedic surgery type

Secondary outcomes

  1. Presence and type of comorbidities

    Time frame: 6 month period before operation

    Hypertension, dementia, asthma, COPD (Chronic obstructive pulmonary disease), CHF (Chronic Heart Failure), CAD (Coronary artery disease), DM (Diabetes mellitus), valvular heart disease, history of pulmonary emboli, electrolyte imbalance, presence of cancer, renal diseases, history of cerebrovascular disease, endocrine diseases, neurologic diseases, other chronic diseases

Sponsors and collaborators

Lead sponsor

Istanbul Medeniyet University

Other

Registry information

Official study title

Anesthetic Techniques and Clinical Outcomes in the Oldest-old Patients Operated for Orthopedic Surgery: A Seven-year Retrospective Analysis of Data in a Third Level Hospital

Important dates

Study start
2016
Primary completion
2022
Study completion
2024
First posted
Jul 26, 2024
Registry last updated
Jul 26, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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