Ocular Responses to Short and Long-term Lens Wear

The purpose of this study was to determine whether ocular surface sensitivity to pneumatic, mechanical and chemical stimulation would be affected by the use of the combination of a specific silicone hydrogel lens material with two lens care products over a four week period.

Completed

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Key information

Conditions

Ametropia Eye Diseases Refractive Errors

Age range

17 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Waterloo

Waterloo, Ontario, N2L 3G1, Canada

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Is at least 17 years old and has full legal capacity to volunteer;
Is correctable to a visual acuity of 6/7.5 (20/25) or better (both eyes) with their habitual vision correction;
Is a current soft lens wearer and wears contact lenses six or more days/week;
Has clear corneas and no active ocular disease.

Exclusion criteria

Has any clinically significant blepharitis or dry eye;
Has undergone corneal refractive surgery;
Is aphakic;
Has any active ocular disease;
Has any systemic disease affecting ocular health;
Is using any systemic or topical medications that may affect ocular health;

Treatment and study plan

Purevision Lenses with ReNu Multiplus

Device

Purevision lenses using ReNu Multiplus lens solution for 28 days

Other names: Balafilcon A

Purevision Lenses with Optifree RepleniSH

Device

Purevision lenses using Optifree RepleniSH lens solution for 28 days

Other names: Balafilcon A

Primary outcomes

Quantify the ocular response to acute and chronic lens wear using slit lamp examination, tear assay and corneal sensitivity.

Time frame: 5 months

Sponsors and collaborators

Lead sponsor

Bausch & Lomb Incorporated

Industry

Registry information

Official study title

Ocular Responses to Acute and Chronic Lens Wear

Important dates

Study start: 2008
Primary completion: 2009
Study completion: 2009
First posted: Jul 28, 2008
Registry last updated: Nov 26, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed