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OpenTrials
Completed

NCT Number: NCT05455567

OCTA Study of Choroidal Vasculature in Open Angle Glaucoma Patients

The aim of the present study was to examine and measure SFCT and CCVD using respectively EDI-OCT and OCTA in preperimetric and advanced glaucomatous eyes, in order to shed light on the vascular pathogenesis of glaucoma disease.

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Key information

Conditions

Glaucoma Open-Angle Primary Eye Diseases Glaucoma Glaucoma, Open-Angle Ocular Hypertension

Age range

40 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Naples "Federico II"

Naples, 80100, Italy

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

• age older than 40 years

  • diagnosis of glaucoma
  • absence of diabetes, heart diseases, hypertension
  • absence of drug intake
  • absence of vitreoretinal, vascular retinal diseases
  • absence of previous ocular surgery and congenital eye diseases.
  • absence of errors of refraction
  • absence of lens opacities
  • absence of low-quality OCT and OCTA images

Exclusion criteria

  • age younger than 40 years
  • presence of diabetes, heart diseases, hypertension
  • vitreoretinal and vascular retinal diseases
  • previous ocular surgery and congenital eye diseases
  • errors of refraction
  • lens opacities
  • low-quality OCT and OCTA images

Treatment and study plan

OCTA

Diagnostic Test

Choriocapillary vessel density calculated with OCTA

Primary outcomes

  1. The measurements of choroidal thickness and choriocapillary vessel density in patients with open angle glaucoma.

    Time frame: up to 5 months

    correlation of measurement of choroidal thickness and choriocapillary vessel density in three different patients groups

Sponsors and collaborators

Lead sponsor

Federico II University

Other

Registry information

Official study title

OCTA as a New Biomarker in the Pathogenesis of Primary Open Angle Glaucoma

Important dates

Study start
2022
Primary completion
2022
Study completion
2022
First posted
Jul 13, 2022
Registry last updated
Jul 25, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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