Obstructive Sleep Apnea in Pulmonary Embolism

Obstructive sleep apnea (OSA) is a clinical syndrome characterized by repetitive closure of the airway and frequent awakenings during sleep. Repeated episodes of hypoxia, decrease in intrathoracic pressure, increased venous return and venous stasis, damage to vascular wall may ensue. An increased tendency for coagulation has also been reported in OSA. Venous stasis, vascular endothelial activation and hypercoagulability are also known risk factors for thromboembolism. All of these pathophysiologic changes in OSA may predispose patients for the development of pulmonary embolism (PE) however there is limited data about role of thromboembolic events in OSA.

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Key information

Conditions

Pulmonary Thromboembolism Apnea Behavior Cardiovascular Diseases Coitus Dyssomnias Embolism Embolism and Thrombosis Hematologic Diseases Hemic and Lymphatic Diseases Lung Diseases Nervous System Diseases Obstructive Sleep Apnea Pulmonary Embolism Respiration Disorders Respiratory Tract Diseases Sexual Behavior Sleep Apnea Syndromes Sleep Apnea, Obstructive Sleep Disorders, Intrinsic Sleep Wake Disorders Thrombophilia Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Gaziantep Hospital

Gaziantep, 27310, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All consecutive patients diagnosed with pulmonary embolism

Exclusion criteria

less than 18 years of age
any restrictive or obstructive lung disease

Treatment and study plan

Polysomnography

Other

full night supervised laboratory polysomnography

Other names: PSG

Sponsors and collaborators

Lead sponsor

University of Gaziantep

Other

Registry information

Official study title

Obstructive Sleep Apnea is Prevalent in Patients With Pulmonary Embolism

Important dates

Study start: 2009
Primary completion: 2010
Study completion: 2010
First posted: Apr 18, 2012
Registry last updated: Apr 18, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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