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NCT Number: NCT02829437

Observational Study on Endometrial Stromal Tumors

Observational, retrospective and prospective study on Endometrial Stromal Tumor (EST)

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Key information

Conditions

Endometrial Stromal Tumors Endometrial Neoplasms Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genital Diseases Genital Diseases, Female Genital Neoplasms, Female Neoplasms Neoplasms by Histologic Type Neoplasms, Connective Tissue Neoplasms, Connective and Soft Tissue Sarcoma Urogenital Diseases Urogenital Neoplasms Uterine Diseases Uterine Neoplasms

Age range

18 year–80 year

Sex eligibility

Female

Study type

Observational

Primary location

Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori - IRST, Meldola, FC, Italy

Loading trial locations.

About this study

Observational, retrospective and prospective study on EST aimed to understand more about its biology, natural history and antitumor activity of different treatment options.

This study will collect data in prospective and retrospective way of patients affected by EST and treated according disease guidelines and local practices.

The study will also review the diagnosis by a central expert pathologist in order to its confirmation

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients with a diagnosis of Endometrial Stromal Tumor (EST) according to the World Health Organization (WHO) classification 2003 or 2014
  • Informed consent signature

Exclusion criteria

  • patients with different diagnosis from EST

Treatment and study plan

Treatment for EST

Other

Surgery and/or Chemotherapy and or/radiotherapy for EST treatment according to disease guidelines: no specific treatment is imposed by protocol (observational study)

Primary outcomes

  1. Disease natural history

    Time frame: Through survival, an average of 5 years

    Collection of data on the natural history of endometrial stromal tumors

Secondary outcomes

  1. Disease diagnosis and classification

    Time frame: At the time of diagnosis, an average of 1 month

    Highlight some main issues in pathologic diagnosis of these tumors and their classification

  2. Chemotherapy received treatment

    Time frame: Through treatment completion, an average of 24 month

    Number and type of chemotherapy agents received for EST treatment

Study contacts

Contact information is provided by the study sponsor or research team.

Gianluca Ignazzi, PhD

CONTACT

[email protected]

+393335359192

Sponsors and collaborators

Lead sponsor

Italian Sarcoma Group

Network

Registry information

Official study title

Endometrial Stromal Tumors: an Observational Study

Acronym: EST

Important dates

Study start
2016
Primary completion
2026
Study completion
2026
First posted
Jul 12, 2016
Registry last updated
Jan 2, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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