Observational Study of the Clinico-biological Evolution and Standard of Care Offered to Patients With Ebola Virus Disease

This study highlighted the possibility, even in epidemic settings, of providing advanced supportive care for patients with VMEs. Indeed, while the prospect of offering any invasive medical care was widely discussed in 2014 in West Africa with the aim of limiting the exposure of caregivers, the epidemic of 2018-2019 has on the contrary seen the development of a number of medical care strategies, in parallel with the deployment of specific treatments. This study aims to describe a cohort of patients receiving this upgraded supportive care during the tenth epidemic in the DRC.

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Key information

Conditions

Ebola Virus Disease Filoviridae Infections Hemorrhagic Fever, Ebola Hemorrhagic Fevers, Viral Infections Mononegavirales Infections RNA Virus Infections Virus Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

BENI ETC

Beni, North Kivu, Democratic Republic of the Congo

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Laboratory confirmed Ebola Virus Disease

Exclusion criteria

Treatment and study plan

Standard of care

Other

(i) advanced clinical and biological monitoring system (ii) symptomatic treatment adapted to the patient's needs, such as antibiotic therapy, oxygen therapy and blood transfusion; (iii) dialysis or mechanical ventilation.

Primary outcomes

Mortality

Time frame: Through the end of the hospitalization, with an average of 11 days

Any type mortality during hospitalization

Sponsors and collaborators

Lead sponsor

Alliance for International Medical Action

Other

Registry information

Acronym: EVISTA

Important dates

Study start: 2018
Primary completion: 2019
Study completion: 2019
First posted: Mar 24, 2021
Registry last updated: Mar 24, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed