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NCT Number: NCT05643014

Observational Study of Exposure to Environmental Toxicants Among Firefighters

Observational, within subject study design with 1 pre and 2 post-fire exposure biomarker samples collected to assess exposure to toxicants from combustion emissions related to fighting a structural fire.

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Key information

Conditions

Healthy

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Firefighter (career or volunteer)
  • Over 18 years of age
  • Able to provide written voluntary consent

Exclusion criteria

  • Unwilling to provide a pre and post-exposure urine sample
  • Current cancer diagnosis
  • Tobacco use within the last 1 year (verified by urinary TNEs)

Treatment and study plan

Sample collection

Other

This study will involve three sample collections including buccal cells and urine samples

Primary outcomes

  1. Studying biomarker levels in firefighters pre and post fire call.

    Time frame: 48 months

    The investigators will evaluate the differences between mean pre-exposure biomarker levels and post-exposure levels in urine and buccal samples collected within 24 hours post-exposure and 1-week post-exposure respectively using t-tests to test for statistical significance.

Study contacts

Contact information is provided by the study sponsor or research team.

Joni Jensen

CONTACT

[email protected]

612-624-5178

Sponsors and collaborators

Lead sponsor

Masonic Cancer Center, University of Minnesota

Other

Registry information

Official study title

Evaluate the Exposure to Toxicants Emitted During a Structural Fire Assessed by Urinary and Buccal Cell Biomarkers Found in Firefighters.

Important dates

Study start
2020
Primary completion
2026
Study completion
2027
First posted
Dec 8, 2022
Registry last updated
Mar 12, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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