Observational Prospective Study.at the End of the Study the Patients Will be Classified According to PH,Serum Bicarbonate and Serum Sodium Into 6 Groups and Statistical Analysis Will be Performed Using Spss

1-to identify the prognostic value of serum bicarbonate and serum electrolytes at time of admission and their association with development of complications ,length of hospital stay ,prognosis and mortality in hospitalized cirrhotic patient

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Key information

Conditions

Liver Cirrhosis Digestive System Diseases Fibrosis Liver Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Heba Allah fadel abd elrahman

Sohag, Egypt

About this study

the purpose of this study will be explore the impact of data obtained for the arterial blood gas parameters and serum bicarbonate and electrolytes at the time of hospital admission on adverse clinical outcomes ,duration of length of hospital stay and mortality in patients with cirrhosis .Furthermore incorporation these parameters into model of end stage liver disease could help to improve the prognostic value of MELDscore in comparison to the prognostic value of traditional equation of original MELD and child score

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

patients with confirmed diagnosis of cirrhosis (age >18 years ) who will be admitted to internal medicine department or will be admitted to intermediate care unit

willing and agree to be included in the study

Exclusion criteria

patients without evidence of cirrhosis
cirrhotic patients whom -younger than 18 years old

have diabetic ketoacidosis
with acute coronary syndrome
with fulminant liver failure
with heart failure
with organ transplantation
when arterial blood gases not be available
patient refusal
patient with HCC

Treatment and study plan

arterial blood gases and serum electrolytes

Diagnostic Test

arterial bloog gases parameters serum potassium serum sodium serum calcium

Primary outcomes

will be ICU admitted

Time frame: from the day of admission to the day of discharge from hospital or death during hospitalization

will be admitted to ICU due to progression of the disease

complications as shok,hepatorenal syndrome,severe infection,starting renal replacement therapy and icu intervention as mechanical ventilation using MELD score and child score depending on ABGparameters and serum electrolytes .

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Impact of Serum Bicarbonate and Electrolytes on Adverse Outcomes in Decompensated Cirrhotic Patients in Sohag University Hospital

Important dates

Study start: 2021
Primary completion: 2022
Study completion: 2023
First posted: Oct 18, 2021
Registry last updated: Jan 10, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed