Obesity and Mortality

Previous analyses of the National Health and Nutrition Examination Survey have suggested that the mortality rate associated with obesity has decreased over calendar time in the U.S. population, potentially due to improvements in the medical care of obesity and its associated diseases. The primary aim of this project is to evaluate whether this reduction in the detrimental association of obesity with mortality rate over calendar time is supported by other data from U.S. prospective studies.

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Key information

Conditions

Obesity and Overweight Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

U.S. based studies with at least 1500 subjects
At least 5 years of mortality follow-up
BMI measured or self-reported available at 2 or more separate calendar time
Subjects varied in age at baseline

Exclusion criteria

Any study that does not meet the inclusion criteria was excluded

Treatment and study plan

Primary outcomes

Change in Years of Life Lost Associated with Standard BMI categories Over Calendar Time

Time frame: Between 1960 and 2000 (up to 40 years)

Secondary outcomes

Change in Adjusted Hazard Ratio Over Calendar Time for Standard BMI Categories

Time frame: Between 1960 and 2000 (up to 40 years)

Sponsors and collaborators

Lead sponsor

University of Alabama at Birmingham

Other

Collaborators

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Registry information

Important dates

Study start: 2008
Primary completion: 2013
Study completion: 2013
First posted: Jun 28, 2013
Registry last updated: Aug 25, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed