Hull University Teaching Hospitals NHS Trust
Hull, E. Riding Yorkshire, HU16 5JQ, United Kingdom
Location status: Recruiting
Location contact
James P Hobkirk, PhD
CONTACT
James P Hobkirk, PhD
PRINCIPAL_INVESTIGATOR
Mahmoud M Loubani, MD
CONTACT
Recruiting
NCT Number: NCT07409519
Nutritional Screening in Cardiovascular Disease
This is a nutritional screening and assessment study conducted prior to heart surgery. The nutritional status of patients will be assessed by a series of questionnaires, blood/urine biomarkers and measurement of grip strength and body composition. The investigators will then evaluate of any of the assessments are linked with clinical outcomes following surgery. For example, how long do patients stop in the intensive care unit (ICU), in hospital and how many complications patients experience.
The investigators hope to use this important clinical data to understand how medical staff can identify a poor nutritional status and which patients may need nutritional support prior to surgery.
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
40 year–85 year
Sex eligibility
All sexes
Study type
Observational
Primary location
About this study
This is a cross sectional nutritional screening and assessment study conducted prior to cardiac surgery . The investigators will focus on comparing aspects of nutritional status with robust and validated clinical outcomes (mechanical ventilation, ICU time, hospital stay and Society of Cardiothoracic Surgery (SCTS) complications). The investigators will utilise various nutritional screening questionnaires and assessments, including routine clinical malnutrition tools (i.e. MUST, NRS), plus more nutritional quality assessments such as the NOVA ultra-processed food intake, mediterranean diet and blood biomarker panels such as the Prognostic Nutritional Index (PNI), Controlling Nutritional Status (CONUT).
The investigators will also undertake a functional grip strength test and measure body composition including fat mass (FM) & fat-free mass (FFM), segmental analysis, sarcopenic obesity and visceral fat. The study will also conduct questionnaires regarding other lifestyle related factors (sleep, recent physical activity, stress, anxiety, depression) which might also influence surgical outcomes.
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- No pre-specified inclusion criteria to ensure we recruit a representative group of patients.
Exclusion criteria
- All patients without proficiency in English that allows completion of questionnaires
- Unable to provide written consent
Treatment and study plan
Nutritional Screening
BehavioralTo identify which nutritional screening approaches (nutritional questionnaires, biomarkers, sarcopenic obesity or grip strength are most strongly linked to surgical outcomes following cardiac surgery.
Primary outcomes
-
Time in ICU
Time frame: From ICU admission until ICU discharge, up to 30 days
The total time in hours spent in the ICU, calculated from ICU admission following cardiac surgery to ICU discharge to the general cardiology ward
-
Complications post cardiac surgery
Time frame: Number of complications following cardiac surgery, up to 30 days
The number of Society of Cardio-thoracic Surgery register of complications
-
Length of Hospital Stay
Time frame: From hospital admission until hospital discharge, up to 30 days
Length of hospital stay from admission to medical discharge
Study contacts
Contact information is provided by the study sponsor or research team.
James P Hobkirk, PhD
CONTACT
Mahmoud M Loubani, MD
CONTACT
Sponsors and collaborators
Lead sponsor
Hull University Teaching Hospitals NHS Trust
Other Gov
Registry information
Official study title
Nutritional Screening in Patients With Cardiovascular Disease
Acronym: NS
Important dates
- Study start
- 2025
- Primary completion
- 2026
- Study completion
- 2027
- First posted
- Feb 13, 2026
- Registry last updated
- Jun 23, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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