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NCT Number: NCT06510712

Nutritional Risk for Hospitalized Patients With Neurology Disorders in China

Neurology disorders are one of the major public health problems that seriously threaten human health. It often accompanied by various nutritional problems, which can aggravate the primary disease, lead to serious complications, prolong the hospitalization, lead to poor prognosis, and increase family and social economic burdens. According to the previous studies, the risk of malnutrition was approximately 58.5% of stroke patients, and 6% had moderate to severe malnutrition in China. Another study conducted in Beijing showed that the risk of malnutrition of elderly patients in the department of neurology was significantly higher than in other departments (28.5% vs. 26.4%). Strengthening nutritional supervision of patients with neurology disorders will benefit to improve patients' prognosis. Therefore, the aim of this study is to investigate the nutritional status of inpatients with neurology disorders in China, evaluate the impact of different nutritional status on patients' health outcomes, and establish a high-quality, standardized nutrition and health cohort database for neurology disorders.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥ 18 years;
  • The primary diagnosis was neurological disorders;
  • Written informed consent.

Exclusion criteria

  • Life expectancy is < 3 months;
  • Researchers think other ineligible participant for the study.

Treatment and study plan

Primary outcomes

  1. All-cause mortality

    Time frame: 30 days

    Mortality defined as all-cause mortality from inclusion to day 30

Secondary outcomes

  1. ICU admission

    Time frame: 30 days

    ICU admission defined as admission to the intensive care unit from the medical ward from inclusion to day 30

  2. Non-elective hospital readmission

    Time frame: 30 days

    Non-elective hospital readmission defined as non-scheduled hospital readmission after discharge from the index hospital stay to day 30

  3. Major complications

    Time frame: 30 days

    Major complications defined as the following complications occurring from inclusion (i.e., not present at the time of inclusion) to day 30 I. Adjudicated nosocomial infection or abscess requiring antibiotic treatment II. respiratory failure with need for invasive or non-invasive ventilation III. major cardiovascular events including stroke, intracranial bleeding, cardiac arrest, myocardial infarction with and without invasive procedure and pulmonary embolism IV. acute renal failure (defined by 2x increase of baseline creatinine or new requirement of dialysis do to volume overload or electrolyte disturbance) V. gastro-intestinal events (hemorrhage, intestinal perforation)

  4. Decline in functional status of 10% or more

    Time frame: 30 days

    decline in functional status of 10% or more from admission to day 30 measured by the Barthel's index.

  5. length of in hospital days

    Time frame: 30 days

    Total length of in hospital days 30 days

Other outcomes

  1. Adverse events

    Time frame: 30 days

    Each of the adverse events

Study contacts

Contact information is provided by the study sponsor or research team.

Gaoting Ma, PhD

CONTACT

[email protected]

18301579891

Sponsors and collaborators

Lead sponsor

Xuanwu Hospital, Beijing

Other

Registry information

Official study title

Nutritional Risk and Health Research for Hospitalized Patients With Neurology Disorders in China

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Jul 19, 2024
Registry last updated
Jul 19, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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