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Completed

NCT Number: NCT07289867

Nutritional Effects of Supplementing Nonagenarians With a Supplement Based on a Fruit From the Cerrado: Buriti

The population aged over 90 is growing worldwide, and the search for strategies to promote a better quality of life for the older persons is a challenge for science. Advancing age is associated with several physiological changes leading to different diseases, among which malnutrition and sarcopenia stand out. Malnutrition prevention and treatment are based on functional food/nutritional interventions, such as oral supplement use. However, studies evaluating the effectiveness of these supplements in nonagenarians are still scarce in the literature. The present study aimed to evaluate the use of a buriti fruit (Mauritia flexuosa) supplement in persons 90 years and older. The study included 40 individuals who were randomized into two groups. The group Supplement Test (ST) used a Buriti-based supplement with full vitamins and minerals; the control group used a capsule containing the same composition of vitamins and minerals as the test supplement, which was called Vitamin Mix (VM). The intervention lasted 12 weeks. The following analyses were carried out before and after this period: Mini Nutritional Assessment (MNA) questionnaire, handgrip strength (HGS), biochemical tests, and anthropometric measurements. The main results showed that the Buriti supplement led to a significant increase in body weight, Body Mass Index (BMI), handgrip strength, and globulins, when compared to the group that used the vitamin mix. Therefore, it can be concluded that the buriti supplement promotes an improvement in body composition, increased strength, and globulins in nonagenarians, and may be a viable and effective strategy for malnutrition treatment.

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Key information

Age range

90 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

State University of Minas Gerais

Montes Claros, Minas Gerais, Brazil

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Participants aged 90 or over were selected from the database of the Reference Center for Elderly Health Care in Montes Claros, MG .

Exclusion criteria

  • Exclusion criteria included severe obesity, decompensated chronic diseases, or inability/refusal to consent.

Treatment and study plan

Nutricer Energia Zero-lactose

Dietary Supplement

Daily administration of two tablespoons of solubilized in whole milk once a day for 3 months.

Other names: Supplement Group

Multivitamin Mix

Dietary Supplement

Daily administration of one multivitamin capsule for 3 months.

Other names: Control Group (Multivitamin Mix)

Primary outcomes

  1. Change in Body Weight

    Time frame: Baseline and after 12 weeks of supplementation

    Body weight (kg) was measured using a calibrated digital scale to evaluate changes after supplementation.

  2. Change in Muscle Strength

    Time frame: Baseline and after 12 weeks of supplementation.

    Muscle strength was assessed using a handgrip dynamometer to evaluate functional improvement following 12 weeks of supplementation.

Secondary outcomes

  1. Change in Body Weight

    Time frame: Baseline and after 12 weeks of supplementation

    Body weight (kg) was measured using a calibrated digital scale to assess changes in body mass after supplementation.

  2. Change in Body Mass Index

    Time frame: Baseline and after 12 weeks of supplementation.

    BMI (kg/m²) was calculated as weight divided by height squared to evaluate body composition changes.

  3. Change in Serum Globulin Levels

    Time frame: Baseline and after 12 weeks of supplementation.

    Serum globulin concentration (g/dL) was determined using standard biochemical methods to assess protein metabolism changes.

Sponsors and collaborators

Lead sponsor

Federal University of Minas Gerais

Other

Registry information

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Dec 17, 2025
Registry last updated
Dec 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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