Nutrient Levels Alter Transplant Outcome

The purpose of this study is to look at lipid profiles of plasma and RBC and amino acid profiles in plasma to determine if they are associated with allograft rejection, calcineurin inhibitor toxicity or new onset diabetes mellitus in renal transplant patients receiving dietary supplements with arginine and omega-3 fatty acids.

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Key information

Conditions

Chronic Renal Disease Chronic Disease Disease Attributes Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Diseases Male Urogenital Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Renal Insufficiency Renal Insufficiency, Chronic Urogenital Diseases Urologic Diseases

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Washington Hospital, Washington D.C., District of Columbia, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Renal transplant recipient
Appropriate blood samples drawn and analyzed

Treatment and study plan

Arginine and canola oil

Dietary Supplement

Canola oil 1 tablespoon BID Arginine 9.0grams BID

Other names: Arginaid

Coromega and Arginine

Dietary Supplement

Arginine 9.0 grams BID Coromega dose based on weight

Other names: Arginaide

Primary outcomes

Plasma and red blood cell lipid profiles

Time frame: Within 1 year
Plasma amino acid profiles

Time frame: within 1 year

Sponsors and collaborators

Lead sponsor

University of Cincinnati

Other

Collaborators

National Institutes of Health (NIH)

Registry information

Official study title

Role of Immunonutrient Levels in Preventing Complications After Renal Transplantation

Important dates

Study start: 1997
Study completion: 2005
First posted: Nov 19, 2007
Registry last updated: Nov 19, 2007

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed