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Completed

NCT Number: NCT02863341

Nursing Home Team-Care Deprescribing Study

This is a multi-centre study in Singapore nursing homes, investigating the factors that affecting deprescribing, and if a team-care based deprescribing standard practice gives superior health and pharmacoeconomic outcomes over current medication review practice.

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Key information

Conditions

Fall in Nursing Home Medication Therapy Management

Age range

65 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Nursing homes

Singapore

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

For interview questionnaire:

Inclusion criteria

are:

  • Accepted informed consent,
  • The healthcare professional is practicing in the involved nursing homes.

Exclusion criteria

are:

  • Decline/unable to provide consent.

For team-care deprescribing study:

Inclusion criteria

are:

  • Accepted informed consent (unless cognitive-impaired, with no or un-contactable next-of-kin),
  • Adult aged 65 years and above,
  • Currently on five or more medications.

Exclusion criteria

are:

  • Below the age of 65 years of age,
  • Life expectancy of less than 6 months or respite care.

Treatment and study plan

Team-care deprescribing with deprescribing guide

Other

Beers criteria 2015, STOPP criteria 2014, drug interaction

Primary outcomes

  1. Change from baseline in Fall Risk Assessment Tool (FRAT) score

    Time frame: Change from baseline in FRAT score at 3 months

  2. Change from baseline in Fall Risk Assessment Tool (FRAT) score

    Time frame: Change from baseline in FRAT score at 6 months

  3. Change from baseline in Fall Risk Assessment Tool (FRAT) score

    Time frame: Change from baseline in FRAT score at 12 months

  4. Change from baseline in fall rate

    Time frame: Change from baseline in fall rate at 3 months

  5. Change from baseline in fall rate

    Time frame: Change from baseline in fall rate at 6 months

  6. Change from baseline in fall rate

    Time frame: Change from baseline in fall rate at 12 months

Secondary outcomes

  1. Factors affecting deprescribing

    Time frame: 0 month

    Interview questionnaire

  2. Change from baseline in mean number of medications per subject

    Time frame: Change from baseline in mean number of medications per subject at 3 months

  3. Change from baseline in mean number of medications per subject

    Time frame: Change from baseline in mean number of medications per subject at 6 months

  4. Change from baseline in mean number of medications per subject

    Time frame: Change from baseline in mean number of medications per subject at 12 months

  5. Change from baseline in mean medication cost per subject

    Time frame: Change from baseline in mean medication cost at 3 months

  6. Change from baseline in mean medication cost per subject

    Time frame: Change from baseline in mean medication cost at 6 months

  7. Change from baseline in mean medication cost per subject

    Time frame: Change from baseline in mean medication cost at 12 months

  8. Change from baseline in deprescribing intervention acceptance rate

    Time frame: Change from baseline in deprescribing intervention acceptance rate at 3 months

  9. Change from baseline in deprescribing intervention acceptance rate

    Time frame: Change from baseline in deprescribing intervention acceptance rate at 6 months

  10. Change from baseline in deprescribing intervention acceptance rate

    Time frame: Change from baseline in deprescribing intervention acceptance rate at 12 months

  11. Change from baseline in percentage of drug-related problems (DRPs)

    Time frame: Change from baseline in percentage of DRPs at 3 months

    Medication review form (Hepler/Strand DRP classification system)

  12. Change from baseline in percentage of drug-related problems (DRPs)

    Time frame: Change from baseline in percentage of DRPs at 6 months

    Medication review form (Hepler/Strand DRP classification system)

  13. Change from baseline in percentage of drug-related problems (DRPs)

    Time frame: Change from baseline in percentage of DRPs at 12 months

    Medication review form (Hepler/Strand DRP classification system)

Sponsors and collaborators

Lead sponsor

Tan Tock Seng Hospital

Other

Collaborators

  • Monash University
  • National Healthcare Group, Singapore

Registry information

Important dates

Study start
2016
Primary completion
2018
Study completion
2018
First posted
Aug 11, 2016
Registry last updated
Apr 5, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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