NT-proBNP as a Tool for the Detection of Acute Pulmonary Artery Embolism (APE)

In patients with suspected APE (Acute Pulmonary Embolism) referred to the intensive care unit (ICU)after major surgery, serum NT-proBNP (N-terminal proBNP), Troponin-I and D-dimers were measured according to the standard hospital protocol. To definitively confirm or exclude APE, all patients underwent an angiographic CT-scan of the thorax.

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Key information

Conditions

Pulmonary Embolism Cardiovascular Diseases Embolism Embolism and Thrombosis Lung Diseases Pulmonary Embolism Without Mention of Acute Cor Pulmonale Respiratory Tract Diseases Vascular Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Ulm, Michelsberg anaesthesiologic ICU

Ulm, Baden-Wurttemberg, 89075, Germany

About this study

In patients with suspected APE referred to the intensive care unit after major surgery, serum NT-proBNP, Troponin-I and D-dimers were measured according to the standard hospital protocol. Blood samples were obtained within one hour after the onset of clinical symptoms.

Definitive confirmation or exclusion of APE was performed with an angiographic CT-scan of the thorax.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

all patients referred to the ICU with suspected APE

Exclusion criteria

none

Treatment and study plan

Primary outcomes

Acute pulmonary embolism: CT-proof yes vs. no

Time frame: 1 hour after onset of clinical symptoms

Sponsors and collaborators

Lead sponsor

University of Ulm

Other

Registry information

Official study title

NT-proBNP: a Useful Tool for the Detection of Acute Pulmonary Artery Embolism in Post-surgical Patients

Important dates

Study start: 2008
Primary completion: 2011
Study completion: 2011
First posted: Jul 4, 2012
Registry last updated: Jul 6, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed