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NCT Number: NCT06877182

Novel Neuroradiological Workflow for the Assisted DIAgnosis and Management of DEMentia with Artificial Intelligence

Identifying, screening and monitoring individuals at risk of Alzheimer's disease (AD) and dementia is a formidable challenge. Neuroimaging, and in particular magnetic resonance imaging (MRI), is crucial to detect structural neurodegeneration. However, current quantification tools are mainly limited to research contexts and produce non-standardised results. DIADEMA will build a systematic and standardised workflow to support neuro(radio)logical diagnosis. By combining artificial intelligence (AI) and machine learning (ML) the investigators will significantly enhance the clinical diagnosis of AD in neuroradiology. The investigator's main hypothesis is that an efficient workflow and associated higher diagnostic accuracy will substantially reduce healthcare costs, support clinical decision-making, provide second-opinion tools and improve patient care. This dual advance will have a profound impact on the healthcare system, marking an important step in the fight against Alzheimer's disease and dementia.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Sex eligibility

All sexes

Study type

Observational

Primary location

Irccs Synlab Sdn

Naples, 80146, Italy

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients who perform brain magnetic resonance during the last 20 years

Exclusion criteria

-

Treatment and study plan

Magnetic Resonance Imaging with Contrast

Diagnostic Test

To evaluate the possibility to improve the neuroradiologic workflow with AI models

Primary outcomes

  1. Improvement of the neuroradiological workflow performance

    Time frame: 1-36 month

    ROC curves

Sponsors and collaborators

Lead sponsor

IRCCS SYNLAB SDN

Other

Collaborators

  • Ospedale Fate bene Fratelli di Brescia
  • UNINA
  • UNITO

Registry information

Acronym: DIADEMA

Important dates

Study start
2024
Primary completion
2025
Study completion
2027
First posted
Mar 14, 2025
Registry last updated
Mar 19, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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