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Completed

NCT Number: NCT02834832

Novel Coating to Minimize Bacterial Adhesions and Tooth Wear in Denture Acrylic

This study evaluates the effect of coatings on bacterial adhesion on denture acrylic and the wear of denture teeth.

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Key information

Conditions

Denture Stomatitis Mouth Diseases Stomatitis Stomatitis, Denture Stomatognathic Diseases Wear of Denture Teeth

Age range

21 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Florida

Gainesville, Florida, 32610, United States

About this study

Denture stomatitis is a prevalent disease among removable denture wearers. The cause of this disease stems from a myriad of factors including host immunity and poor oral hygiene. Denture acrylic material is very conducive for the growth and adhesion of bacteria because of its porous nature. The application of plasma enhanced chemical vapor deposited (PECVD) coatings on the surface of acrylic dentures can produce a less porous surface which may minimize the adhesion of bacteria and therefore colonization. The goal is the application of these coatings will help minimize the occurrence of denture stomatitis.

Another issue of removable dentures is the low wear resistance of denture teeth. The application of these coatings on denture teeth should minimize wear of these teeth and prolong the life of removable dentures.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who are missing some teeth and will need removable dentures

Exclusion criteria

  • Medical contraindication for dental treatment

Treatment and study plan

PECVD coating

Device

SiO2/SiC coatings will be applied to the surface of removable partial dentures and denture teeth.

Primary outcomes

  1. Change in Bacterial Count

    Time frame: 2,4 and 12 weeks

    Biofilms on the tissue surface of the dentures will be obtained for the aforementioned time intervals. Biofilm counts will be analyzed to determine the effect of the coatings on the number of disease causing bacteria on the surface of the denture

Secondary outcomes

  1. wear of denture teeth

    Time frame: 6 months

    Denture teeth will be analyzed for wear at 6 months to determine the effect of PECVD coatings on the wear of denture teeth.

Sponsors and collaborators

Lead sponsor

University of Florida

Other

Registry information

Important dates

Study start
2016
Primary completion
2019
Study completion
2019
First posted
Jul 15, 2016
Registry last updated
Jul 23, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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