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NCT Number: NCT07275619

Normative Data for Cardiorespiratory Fitness in Healthy Adults

Cardiorespiratory fitness (CRF) is a physical attribute which represents how effectively various bodily systems work together to transport and utilize oxygen to support muscular activity during prolonged, rhythmic, large-muscle, whole-body exercise. A key element associated with physical fitness is VO2max, which is referred to as cardiorespiratory fitness. Queen's college step test will be used to estimate the VO2max. This study will be cross sectional, normative study. Healthy adults aged 18-65 years from community setting will be recruited through non probability convenient sampling technique to collect data as per inclusion criteria. Sample size will be approximately 800, consist of equal ratio of males and females. Heart Rate, Recovery Heart Rate, VO2 max and METS will be calculated of each subject. Following equation is used to calculate VO2max, for females: VO2max = 65.81- [0.1847× HR] for males: VO2max = 111.33- [0.42× HR]. Data analysis will be conducted by using SPSS (Statistical Package for the Social Sciences) version 28.

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Key information

Conditions

Healthy Adults

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Riphah International University, Lahore

Lahore, Punjab Province, 54000, Pakistan

About this study

Cardiorespiratory fitness (CRF) is a physical attribute which represents how effectively various bodily systems work together to transport and utilize oxygen to support muscular activity during prolonged, rhythmic, large-muscle, whole-body exercise. A key element associated with physical fitness is VO2max, which is referred to as cardiorespiratory fitness. Queen's college step test (reliability = 0.92, validity = 0.75) will be used to estimate the VO2max. The objectives of the study is to obtain the normative reference values for cardiorespiratory fitness in healthy pakistani adults.

This study will be cross sectional, normative study. Healthy adults aged 18-65 years from community setting will be recruited through non probability convenient sampling technique to collect data as per inclusion criteria. Sample size will be approximately 800, consist of equal ratio of males and females. Heart Rate, Recovery Heart Rate, VO2 max and METS will be calculated of each subject. Following equation is used to calculate VO2max, for females: VO2max = 65.81- [0.1847× HR] for males: VO2max = 111.33- [0.42× HR]. Demographics include Age (years), Height (m2), Weight (kg) and Body Mass Index (BMI kg/m2) will be measure for each subject.Data analysis will be conducted by using SPSS (Statistical Package for the Social Sciences) version 28.

Key words:

Adults, Cardiorespiratory fitness, Normative, Queen's college step test, VO2max

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • • Pakistani Adults of age group 18-65 according to ACSM's guidelines
  • Current healthy adults recruited by filling PAR_Q test
  • IPAQ short form will be administered, Participants scoring moderate or high activity level will be selected to perform QCST
  • BMI ≥ 18.5 kg/m2 - ≤ 24.9 kg/m2
  • Resting spO2 >95%
  • Resting heart rate ≥60bpm and ≤100bpm
  • Mentally and physically fit adults without any physical, physiological and psychological issues

Exclusion criteria

Presence of any acute/chronic illness Any cardiovascular, respiratory, neuromuscular, psychological, musculoskeletal or orthopedic condition and history of surgery Individuals taking any medical treatment History of active smoking

Treatment and study plan

Primary outcomes

  1. Queen's college step test

    Time frame: one time point

    QCST will be used to estimate the VO2max. The step test will be performed using a tool of 16.25 inches height. Stepping will be performed for a total duration of 3 minutes at the rate of 22 steps per minute for females and 24 steps per minute for males which will be set by a metronome. After completing the stepping , the subject remains standing, wait 5 seconds, take a 15s heart rate count and multiply the HR by 4 to convert into beats per minute. following equation is used to predict VO2max.

    For females: VO2max = 65.81- [0.1847× HR] For males: VO2max = 111.33- [0.42× HR] The reliability and validity of queen's college step test is 0.92 and 0.75 respectively.

  2. pulse oximeter

    Time frame: one time point

    Heart rate will be calculated by pulse oximeter. After completing the stepping , the subject remains standing, wait 5 seconds, take a 15s heart rate count and multiply the HR by 4 to convert into beats per minute.

  3. Recovery Heart Rate

    Time frame: one time point

    Recovery heart rate will be measure by substracting the heart rate after 1 minute from the peak heart rate which will be compare with standard values to check the heart health.

  4. METS

    Time frame: one time point

    Metabolic equivalents of task (METS) will be calculated dividing VO2max by 3.5ml/kg/min.

    METS = VO2 MAX ÷ 3.5 ml/kg/min

Secondary outcomes

  1. stadiometer

    Time frame: one time point

    height (m2) will be measure through stadiometer

  2. weighing machine

    Time frame: one time point

    weight (kg) will be measure through weighing machine

  3. Body Mass Index

    Time frame: one time point

    BMI will be calculated dividing weight by height (m2).

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Normative Data for Cardiorespiratory Fitness in Healthy Adults Using the Queen's College Step Test

Acronym: NDFCFIHAUTQCST

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Dec 10, 2025
Registry last updated
Dec 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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