Normal Variability of Tidal Breathing Flow-volume Curves During Sleep in Healthy Children

Impedance pneumograpy results in healthy children to generate normal values and to stude the effect of age and gender

Inclusion criteria

• Age 12 months-71 months, both sexes
• Healthy at the time of inclusion
• Signed informed consent

Exclusion criteria

• Preterm birth
• Recurrent bronchitis or recurrent hospitalizations because of a respiratory illness
• Nasal congestion, adenotonsillar hypertrophy, signs and symptoms of sleep apnea or sleep disordered breathing
• Acute respiratory infection or hospitalization because of an acute illness within 4 weeks prior to inclusion
• Personal or family history of asthma
• Recurrent wheezing without respiratory infection
• Allergic rhinitis, chronic rhinosinusitis, or other chronic respiratory disorders
• Atopic dermatitis
• Diagnosed allergic sensitization
• Use of asthma rescue or maintenance medication within 4 weeks prior to inclusion
• Any major chronic illness as judged by the investigators
• Implanted or external active medical devices such as pacemakers