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OpenTrials
Completed

NCT Number: NCT04144465

Noradrenaline Infusion Versus Phenylephrine Infusion in Improving Serum Lactate Level in HIPEC

ABG PARAMETERS ARE CHANGED DURING HIPEC, WE TRIED TO FIND COMPARISON BETWEEN NORADRENALINE AND PHENYLEPHRINE IN OPTIMIZING ABG PARAMETERS THAT REFLECTS ORGAN PERFUSIONS ESPECIALLY SERUM LACTATE

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Key information

Conditions

Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

Age range

35 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Suez Canal University

Ismailia, 41511, Egypt

About this study

Arterial blood gas testing is considered one of the most important and widely used test in the detection of acidosis, alkalosis, electrolytes disturbance and tissue perfusion. in regard to tissue perfusion serum lactate above 4 mmol/L indicates poor tissue perfusion. serum lactate could be measured at ABG or separately. in this study we will test the effect of both noradrenaline and phenylephrine on lactate level at ABG during the stage of HIPAC in managing abdominal cancer patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • CANCER PATIENTS ENROLLED FOR HIPEC

Exclusion criteria

  • DRUG SENSITIVITY

Treatment and study plan

Noradrenalin

Drug

DRUG THAT IS IMPROVING TISSUE AND ORGAN PERFUSION

Other names: PERFUSION

Phenylephrine

Drug

DRUG THAT IS IMPROVING TISSUE AND ORGAN PERFUSION

Primary outcomes

  1. SERUM LACTATE IN ABG

    Time frame: IMMEDIATELY POSTOPERATIVELY

    LANDMARK FOR TISSUE AND ORGAN PERFUSION

Sponsors and collaborators

Lead sponsor

Suez Canal University

Other

Registry information

Official study title

Effect of Noradrenaline Infusuion Versus Phenyephrine Infusion in Improving Tissue Perfusion in HIPEC

Important dates

Study start
2019
Primary completion
2023
Study completion
2023
First posted
Oct 30, 2019
Registry last updated
May 29, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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