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OpenTrials
Completed

NCT Number: NCT07094620

Non-surgical Rhinoplasty After Nasal Skin Cancer Reconstruction: Enhancing Aesthetic Outcomes

Reconstruction of the nasal pyramid after skin cancer is a complex surgery, often involving multiple stages. For some patients, the final result may be considered insufficient, affecting their quality of life and leading to social isolation, in addition to requiring numerous surgeries. In this context, and with the expertise of our department in this field, patients may benefit from touch-ups using hyaluronic acid, which can improve the outcome without the need for major and costly surgery. This product has the advantages of being accessible, easy to use, and has demonstrated long-term safety in the literature.The aim of the study is to evaluate, in this context, the benefit of medical rhinoplasty as perceived by the patients, as well as to measure the objective volumetric gain using 3-D photography. It also seeks to encourage professionals in this type of surgery to assess the results and motivate them to train in these techniques.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU NICE

Nice, Alpes Maritimes, 0600, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • A history of nasal skin carcinoma treated surgically with reconstruction, a minimum of one year since the last oncologic surgery, a patient-expressed desire for aesthetic improvement, and either refusal of further surgery or a context in which surgical revision was uncertain or not recommended

Exclusion criteria

  • Any standard contraindications to hyaluronic acid injections, oncologic surgery performed less than one year prior or with uncertain resection margins, metastatic evolution and cases where surgical correction remained more appropriate and accessible than injection-based management

Treatment and study plan

Non-surgical rhinoplasty

Radiation

Non-surgical rhinoplasty using hyaluronic acid at baseline consultation.

Primary outcomes

  1. Evaluation of FACE-Q questionnaire score

    Time frame: Baseline, One month and at Two months

    Face-Q is a validated questionnaire evaluating patients PROMs in aesthetic procedures.

Secondary outcomes

  1. Standardized and 3-Dimensions photographs

    Time frame: Baseline, One month and at Two months

    Standardized photographs taken with a camera

  2. 3-Dimensions photographs

    Time frame: Baseline, One month and at Two months

    3-Dimensions photographs acquired by using the Vectra System with evaluation of volumetric changes

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Nice

Other

Registry information

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Jul 30, 2025
Registry last updated
Jul 30, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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