October University for modern sciences and arts (MSA University)
Giza, 11563, Egypt
Location status: Recruiting
Location contact
Ahmed Reda Abdel Rahman, Professor
CONTACT
Dalia Khorshed principal investigator
CONTACT
Rasha Attia
SUB_INVESTIGATOR
Recruiting
NCT Number: NCT07174752
Non-Submerged De-Epithelialized Free Gingival Graft Versus Conventional Free Gingival Graft
The goal of this (study type: RCT) is to learn if the use of the non-submerged de-epithelized FGG will result in better esthetic outcomes in adults. The main questions that it aims to answer are:
* Does this procedure increase the width of keratinized tissue? * Does this procedure increase the depth of the vestibule? Researchers will compare this technique with the gold standard using the FGG to evaluate which technique provides better esthetics.
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
18 year and older
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Adult patients: 18-60.
- Insufficient width of keratinized mucosa, that is less than 2 mm.
- Lower anterior areas.
- Good oral hygiene.
Exclusion criteria
- Systemic conditions that prevent the patient from undergoing minor oral surgical procedures or hinder the healing process.
- Patient undertaking radiotherapy or chemotherapy.
- Smokers.
- Pregnant females
Treatment and study plan
Non-Submerged De-Epithelialized Free Gingival Graft
ProcedureThe Free gingival graft will be de-epithelialized and fixed at the recipient site in a non-submerged manner to increase the keratinized mucosa
Conventional FGG
ProcedureThe Free gingival graft will be fixed at the recipient site to increase the keratinized mucosa
Primary outcomes
-
Esthetic Evaluation of Non-Submerged De-Epithelialized Free Gingival Graft (Ns-dFGG) Versus Conventional Free Gingival Graft (cFGG) for the Augmentation of The Keratinized Mucosa
Time frame: 6 months
The professional esthetic evaluation will be done using the root coverage esthetic score (RES) by(Cairo et al.,2009).
Standardized Clinical photographs will be taken at 6 months, where they will evaluate:
Color matching: Score 0, & Score 1: Regarding the color matching to the normal gingiva Soft tissue texture: Score 0, & Score 1: If there is scar formation or keloid appearance Muco-gingival junction (MGJ) alignment: Score 0, & Score 1:If the MGJ is or isn't aligned that of the adjacent teeth
-
Esthetic Evaluation of Non-Submerged De-Epithelialized Free Gingival Graft (Ns-dFGG) Versus Conventional Free Gingival Graft (cFGG) for the Augmentation of The Keratinized Mucosa
Time frame: 6 months
The patient esthetic evaluation will evaluated at 6 months during the follow-up based on the Visual Analogue Scale(VAS). They will select among 100 scores of color matching: Score 0(Very bad) 50(Average) 100(Excellent)
Study contacts
Contact information is provided by the study sponsor or research team.
Sponsors and collaborators
Lead sponsor
October University for Modern Sciences and Arts
Other
Registry information
Official study title
Esthetic Evaluation of Non-Submerged De-Epithelialized Free Gingival Graft (Ns-dFGG) Versus Conventional Free Gingival Graft (cFGG) for the Augmentation of The Keratinized Mucosa: Randomized Controlled Clinical Trial
Acronym: Ns-dFGG; cFGG
Important dates
- Study start
- 2024
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Sep 16, 2025
- Registry last updated
- Sep 16, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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