Centro de Investigación Cínica Avanzada (CICA), Hospital Clinico de la Universidad de Chile
Santiago, RM, 7690306, Chile
NCT Number: NCT03704090
In the world, 230 million surgeries are performed every year and US data indicates that more than a third of patients who undergo surgery are older than 65 years, in which between 10 and 70% develop postoperative delirium (POD). Patients who develop POD have poor outcomes, such as a longer hospital stay, a deterioration in functional and cognitive status, high mortality rates, and an increase in health costs.
Delirium is an entity that in a significant percentage is preventable, thus preventing the development of POD is fundamental. In fact, in older adults hospitalized in the no surgical ward, the implementation of non-pharmacological prevention measures of delirium has consistently shown to significantly prevent the development of this condition. However, limited information is available about the usefulness of non-pharmacological intervention protocols applied in the perioperative context to prevent POD.
The main aim of this project is to determine whether the application of non-pharmacological measures during the perioperative period prevents POD in elderly patients undergoing highly complex elective surgeries.
The hypothesis is that the application of these measures decreases the incidence of delirium in this population.
Looking for future studies?
Notify Me75 year and older
All sexes
Interventional
Not applicable
Santiago, RM, 7690306, Chile
To determine whether non-pharmacological measures decrease the incidence of POD during the perioperative period in elderly patients undergoing highly complex elective surgeries, it will be performed a randomized clinical trial, where two groups of patients older than 75 years undergoing highly complex elective surgeries will be compared:
This study will be carried out in the surgical units of the Hospital Clinico de la Universidad de Chile (HCUCH) and in the Hospital San Jose (HSJ).
The expected result is to demonstrate that the interventions carried out by occupational therapists decrease the incidence of DPO in a significant way in comparison with standard prevention intervention.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Prevention of postoperative delirium by occupational therapy intervention
Prevention of postoperative delirium using standard non-pharmacological prevention measures
Time frame: 5 days
Developing postoperative delirium evaluated by CAM (complete criteria for delirium diagnostic)
Time frame: 5 days
Developing postoperative subsyndromal delirium evaluated by CAM (incomplete criteria for delium diagnostic)
Time frame: 30 days
Number of days between admission and discharge to the hospital
Time frame: 30 days
Percentage of patients who die between the day of surgery and 30 days after surgery
Time frame: 5 days
Severity of delirium will be evaluated with questionnaire CAM-S
Time frame: 5 days
Number of days in which the patients have delirium
University of Chile
Other
Non-pharmacological Prevention of Postoperative Delirium by Occupational Therapy Teams in Patients Older Than 75 Years Undergoing High-risk Elective Surgery
Acronym: PREPODOT
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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