Non-motor Symptoms and Brain Dopamine Transporter Binding

This project aims to clarify the role non-motor symptoms in the development of Parkinson's disease (PD) and to improve diagnostics at very early stages of PD. The project involves multidimensional measures of disease biomarkers together with brain dopamine transporter (DAT) imaging with [123I]FP-CIT single photon emission computed tomography (SPECT).

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Parkinson Disease Basal Ganglia Diseases Brain Diseases Central Nervous System Diseases Movement Disorders Nervous System Diseases Neurodegenerative Diseases Parkinsonian Disorders Parkinsonism Synucleinopathies

Age range

18 year–100 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Male or Female
Age 18-100 years
Referred for clinical DAT SPECT in Turku or Helsinki

Treatment and study plan

DAT SPECT imaging

Other

Primary outcomes

DAT SPECT striatal specific binding ratio

Time frame: Up to 10 years

Sponsors and collaborators

Lead sponsor

Turku University Hospital

Other Gov

Collaborators

Helsinki University Central Hospital

Registry information

Official study title

Non-motor Symptoms and Brain Dopamine Transporter Binding: An Observational Study in Parkinsonism

Acronym: NMDAT

Important dates

Study start: 2015
Primary completion: 2026
Study completion: 2026
First posted: Jan 8, 2016
Registry last updated: Apr 13, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Active, Not Recruiting