Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07424066

Non-invasive Vibratory Stimulation of the Knee Muscles for the Improvement of the Somatosensory Input and Motor Performance

The goal of this interventional cross-sectional study is to evaluate motor responses to non-invasive vibratory stimulation applied to the hamstring muscle tendons in healthy individuals. Knee flexion and extension efforts, in both isometric and concentric contractions, will be tested.

The investigators hypothesize that vibratory stimulation causes an increase in activity in the flexor muscles (hamstrings) and a decrease in the extensor muscles (quadriceps) of the knee in all motor tasks. It follows that during knee flexion (both concentric and isometric), vibratory stimulation should cause an increase in the distance between the angular trajectories of the knee obtained with and without vibratory stimulation (with a positive sign). The increased activity of the hamstring muscles would, in fact, contribute to increasing the velocity of the flexor movement. Conversely, during extensor movements (both concentric and isometric), vibratory stimulation should reduce the instantaneous velocity of the movement, therefore causing an increase in distance (with a negative sign) between the trajectories obtained with and without stimulation.

Participants will be tested using an isokinetic dynamometer and they will be asked to perform the following motor tasks in a random order: concentric knee flexion, concentric knee extension, isometric knee flexion, and isometric knee extension. The dominant limb will be tested, only. The assessment will be performed one time.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Istituto Auxologico Italiano, Clinica Capitanio

Milan, 20122, Italy

Location status: Recruiting

Location contact

Cristiano Alessandro, Engineer

CONTACT

[email protected]

Kevin Soter, M.Sc.

SUB_INVESTIGATOR

Stefano Scarano, MD

PRINCIPAL_INVESTIGATOR

Stefano Scarano, Medical doctor

CONTACT

[email protected]

+3902619116717

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age equal to or greater than 18 years.

Exclusion criteria

  • Neurological disorders.
  • Musculoskeletal injuries, including previous ones, that may compromise the execution of required movements.
  • Cardiorespiratory disorders.

Treatment and study plan

Vibratory stimulation

Device

A vibratory stimulator will be applied to the back of the dominant leg, at the level of the hamstring muscle tendons. The stimulator consists of two small vibrating boxes fixed to the leg by means of an elastic band.

Primary outcomes

  1. Knee angle

    Time frame: Day 1.

    Maximum distance (in degrees) between the knee trajectory obtained with and without vibratory stimulation.

  2. Surface electromyography (sEMG)

    Time frame: Day 1.

    Difference in sEMG between the muscle activity with and without vibratory stimulation, for each muscle (i.e., Quadriceps, Hamstrings, and Plantarflexor muscles).

Study contacts

Contact information is provided by the study sponsor or research team.

Stefano Scarano, Medical Doctor

CONTACT

[email protected]

+3902619116717

Sponsors and collaborators

Lead sponsor

University of Milano Bicocca

Other

Collaborators

  • Istituto Auxologico Italiano

Registry information

Official study title

Stimolazione Vibratoria Non-invasiva Per il Miglioramento Del Ritorno Sensoriale e Della Performance Motoria in Atleti Con Lesione al Legamento Crociato Anteriore

Acronym: VIBMOT

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Feb 20, 2026
Registry last updated
Feb 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.