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Completed

NCT Number: NCT00479804

Non-Invasive Determination of Cardiac Output by Inertgas Rebreathing Method

The cardiac output (CO) is an important parameter in the diagnosis and therapy of cardiac diseases. The current standard methods for the determination of the CO, however, are either invasive (e.g. right heart catheterization) or technically expendable and expensive (magnetic resonance tomography, MRT). The traditional non-invasive methods of determining the CO by rebreathing of carbon dioxide are easily carried out but suffer from methodical inaccuracies. Therefore the aim of the study at hand was to evaluate a new method for determining the CO by means of the inert gas rebreathing method.

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Key information

Age range

14 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

1st Department of Medicine, University Hospital Mannheim

Mannheim, Baden-Wurttemberg, 68167, Germany

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Indication for CMR
  • Ability of following instructions for rebreathing test

Treatment and study plan

inertgas rebreathing

Device

determination of cardiac output by inertgas rebreathing

spirometry

Device

spirometry for testing the ventilatory function

cardiac magnetic resonance imaging (CMR)

Device

CMR examination which delivers the hemodynamic reference parameters

Sponsors and collaborators

Lead sponsor

Universitätsmedizin Mannheim

Other

Registry information

Official study title

Non-Invasive Determination of Cardiac Output by the Inertgas Rebreathing Method Compared With Magnetic Resonance Tomography

Acronym: NICO

Important dates

Study start
2006
Primary completion
2007
Study completion
2007
First posted
May 28, 2007
Registry last updated
Jun 5, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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