Non-interventional Study With Azacitidin (Vidaza®)

Inclusion criteria

• Patients who are not eligible for haematopoietic stem cell transplantation, who are at least 18 years old (no age limit to top) and who have one of the following diseases:

• myelodysplastic syndrome (MDS) with intermediate risk 2 or high risk according to the International Prognostic Scoring System (IPSS)
• chronic myelomonocytic leukemia (CMML) with 10-29% marrow blasts without myeloproliferative disorder
• acute myeloid leukemia (AML) with 20-30% blasts and multilineage dysplasia according to classification of the World Health Organisation (WHO).

Exclusion criteria

• Contraindication according to the summary of product characteristics of Vidaza®
• Signed patient informed consent form is not available
• Patients with advanced malignant hepatic tumors
• Pregnant or nursing women, men and women (of childbearing age) who are unwilling to apply a reliable method of contraception during and up to three months after treatment with Azacitidine
• Necessary or planned treatment with other systemic cytostatics
• Known medical history of severe decompensatoric cardiac insufficiency
• Medical history of clinically unstable cardiac or pulmonary disease
• Known or suspected hypersensitivity to azacitidine or mannitol