Non-contrast 3D MR Angiography for Assessment of the Thoracic Aorta in Pregnancy

Introduction: Native magnetic resonance angiography (MRA) is recommended to assess the thoracic aorta during pregnancy, avoiding the risks of ionising radiation and contrast agent administration. This guidance is however, based only on consensus opinion supported by limited case reports (level of evidence C).

Aim: To evaluate the feasibility of performing native 3D steady-state free-precession (SSFP) MRA in pregnant subjects with inherited aortopathy to guide timing and mode of delivery.

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Key information

Conditions

Magnetic Resonance Imaging Pregnancy

Sex eligibility

Female

Study type

Observational

Primary location

QEHB

Birmingham, United Kingdom

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Any pregnant subject with a history of familial aortopathy

Exclusion criteria

None

Treatment and study plan

Observational

Other

Primary outcomes

Gestation at delivery

Time frame: 40 weeks
Completion of non-contrast 3D MRA aorta

Time frame: 40 weeks

Sponsors and collaborators

Lead sponsor

University Hospital Birmingham NHS Foundation Trust

Other

Registry information

Official study title

Native High-resolution 3D SSFP MR Angiography for Assessment of the Thoracic Aorta in Pregnant Subjects With Familial Aortopathies

Important dates

Study start: 2015
Primary completion: 2016
Study completion: 2016
First posted: Jun 8, 2016
Registry last updated: Nov 10, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed