Nocturnal Hypertension and Nocturia in African American Men

AIMS AND SIGNIFICANCE OF PILOT DATA

Determine:

• The feasibility of Southern California registry as an effective measure to recruit African American men to participate in a new research program.
• If men will comply with the study procedures including Actigraphy and ambulatory blood pressure monitors.
• The within subject coefficient of variation for repeated measures of nocturnal blood pressure by ambulatory blood pressure monitoring, vertical activity at night by Actigraphy monitors.
• Whether the ambulatory Blood pressure itself affects the sleep pattern on Actigraphy.
• Nocturnal systolic blood pressure and nocturnal vertical activity are higher in men with self-reported nocturia ≥2 at night than in men with no reported nocturia.

Purpose:

Obtain key pilot data to show feasibility and document the reproducibility of the proposed measurements.

Inclusion criteria

• African American Men
• Age 35 to 79 year-old
• Able to give informed consent
• Pass the home sleep study
• Willing to wear the wrist Actigraphy monitor for 9 days continuously.
• Willing to wear ambulatory blood pressure monitoring (ABPM) for 48 hours twice during the 9 days of the study period.

Exclusion criteria

• Diabetes Mellitus
• Taking Prostate medication
• Symptoms of prostate disease or urinary urgency
• Sleep apnea

• A neck circumference greater than 17 inches
• Using Continuous Positive Airway Pressure (CPAP)
• History of a diagnosis of Sleep Apnea
• Apnea Hypopnea Index (AHI) > 15 per hour